Browsing OSU - Faculty and Staff Publications by Subject "Rare Diseases"
Now showing items 21-35 of 35
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Plasmodium falciparum: Release of circumsporozoite protein by sporozoites in the mosquito vector
(Elsevier BV, 1992)The release of circumsporozoite (CS) protein by Plasmodium falciparum sporozoites was investigated to identify factors regulating this process within infected Anopheles gambiae mosquitoes. The potential for sporozoites to ... -
Plasmodium falciparum: The population structure of mature gametocyte cultures has little effect on their innate fertility
(Elsevier BV, 1994)In vitro cultured Plasmodium falciparum gametocytes were fed to Anopheles gambiae (G3) mosquitoes to identify parasite population characteristics useful for predicting successful mosquito infections. Parameters were collected ... -
Population dynamics of Plasmodium falciparum sporogony in laboratory-infected Anopheles gambiae
(American Society of Parasitologists, 1992)The population dynamics of cultured Plasmodium falciparum parasites was examined during their sporogonic development in Anopheles gambiae mosquitoes. Estimates of absolute densities were determined for each life stage, and ... -
PPE surface proteins are required for heme utilization by Mycobacterium tuberculosis
(American Society for Microbiology, 2017-03-08)Iron is essential for replication of Mycobacterium tuberculosis, but iron is efficiently sequestered in the human host during infection. Heme constitutes the largest iron reservoir in the human body and is utilized by many ... -
Prior blood feeding effects on susceptibility of Anopheles gambiae (Diptera: Culicidae) to infection with cultured Plasmodium falciparum (Haemosporida: Plasmodiidae)
(Oxford University Press (OUP), 1994)We examined the relative susceptibilities of Anopheles gambiae Giles of different physiological ages to infection with cultured Plasmodium falciparum (Welch). Cohorts of mosquitoes were divided into three groups; one was ... -
Protein complex from human milk enhances the activity of antibiotics and drugs against Mycobacterium tuberculosis.
(American Society for Microbiology, 2019-02)Mycobacterium tuberculosis, the causative agent of human tuberculosis (TB), has surpassed HIV/AIDS as the leading cause of death from a single infectious agent. The increasing occurrence of drug-resistant strains has become ... -
Quantitation of Plasmodium falciparum sporozoites transmitted in vitro by experimentally infected Anopheles gambiae and Anopheles stephensi
(American Society of Tropical Medicine and Hygiene, 1991)The frequency and numbers of Plasmodium falciparum sporozoites transmitted in vitro and corresponding sporozoite loads were determined for experimentally infected Anopheles gambiae and An. stephensi. Geometric mean (GM) ... -
Reverse transcriptase PCR amplification of Rickettsia typhi from infected mammalian cells and insect vectors
(American Society for Microbiology, 1998-06)We developed a reverse transcriptase PCR assay to detect expression of 120- and 17-kDa antigen genes in Rickettsia typhi. Infected Vero cell and flea RNAs were reverse transcribed by using random hexamers. The cDNA was ... -
Risk assessment of flavivirus transmission in Namibia
(Elsevier BV, 2014-05-25)The role of arboviruses causing acute febrile illness in sub-Saharan Africa is receiving more attention. Reports of dengue in tourists were published nearly 10 years ago in Namibia, but the current epidemiology of arboviruses ... -
Role for zinc transporter gene SLC39A12 in the nervous system and beyond
(Elsevier, 2021-10-05)The SLC39A12 gene encodes the zinc transporter protein ZIP12, which is expressed across many tissues and is highly abundant in the vertebrate nervous system. As a zinc transporter, ZIP12 functions to transport zinc across ... -
Role of the Mycobacterium tuberculosis ESX-4 secretion system in heme iron utilization and pore formation by PPE proteins
(American Society for Microbiology, 2023-02-07)Mycobacterium tuberculosis (Mtb) is transmitted through aerosols and primarily colonizes within the lung. The World Health Organization estimates that Mtb kills ~1.4 million people every year. A key aspect that makes Mtb ... -
Shiga toxin 2 overexpression in Escherichia coli O157:H7 strains associated with severe human disease
(Elsevier, 2011-12)Variation in disease severity among Escherichia coli O157:H7 infections may result from differential expression of Shiga toxin 2 (Stx2). Eleven strains belonging to four prominent phylogenetic clades, including clade 8 ... -
Sporogonic development of cultured Plasmodium falciparum in six species of laboratory-reared Anopheles mosquitoes
(American Society of Tropical Medicine and Hygiene, 1994)Sporogonic development of cultured Plasmodium falciparum was compared in six species of Anopheles mosquitoes. A reference species, A. gambiae, was selected as the standard for comparison. Estimates of absolute densities ... -
Sporozoite transmission by Anopheles freeborni and Anopheles gambiae experimentally infected with Plasmodium falciparum
(The American Mosquito Control Association, 1992)A micro-membrane feeding technique was used to evaluate sporozoite transmission for Anopheles freeborni and An. gambiae experimentally infected with Plasmodium falciparum. From cohorts of infected mosquitoes with equivalent ... -
Updated checklist of the mosquitoes of Oklahoma including new state records and West Nile virus vectors, 2003-06
(The American Mosquito Control Association, 2015-12)The mosquito fauna of Oklahoma has not been evaluated since 1965 and no report has been published concerning species associated with urban areas in the state. Mosquito collections were conducted as part of the West Nile ...