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Multiple species comparative analysis of human chromosome 22 between markers D22S1687 and D22S419 and gene expression profiling in zebrafish.
(2006)
Major large scale insertions or deletions that resulted in gene number differences between human and chimpanzee were discovered in the IGLL and LCR22s within this region, with four human insertions from 6 Kb to 75 Kb and ...
The kinetic and chemical mechanism of serine acetyltransferase from Haemophilus influenzae.
(2004)
The pH dependence of kinetic parameters was determined in both reaction directions in order to obtain information on the acid-base chemical mechanism of serine acetyltransferase from Haemophilus influenzae ( HiSAT). The ...
Dissecting the reaction mechanism of sheep liver 6-phosphogluconate dehydrogenase.
(2000)
In the second part of the research, three additional mutants, S 128A, H 186A and N187A were characterized in the same manner as the K183 mutant enzymes. The decrease in the activity compared to the wild type enzyme is about ...
I. COMPARATIVE STUDY OF LIPIDS OF SHARK LIVERS. II. COMPARATIVE BIOCHEMICAL STUDY OF SOME GORGONIANS.
(1980)
Diterpenoid compounds, cetyl palmitate and hydrocarbons were examined from eggs of Pseudopterogorgia americana and five samples of Plexaura. Two diterpenoid compounds, mw 304 and 306, were obtained only from P. "REM" St. ...
Concise synthesis methods to aminosterols and sterol N-glycosides for the development of new OSW-1-derived scaffolds
(2020-05-08)
Abstract
The cholestane glycoside natural product compound OSW-1 has both broad spectrum antiviral activity and potent antiproliferative activity. OSW-1 is a high affinity ligand of both oxysterol-binding protein (OSBP) ...
THE BIOCHEMICAL CHARACTERIZATION OF TWO PHOSPHORELAY SIGNALING PROTEINS: YPD1 HOMOLOGS FROM SACCHAROMYCES CEREVISIAE AND CRYPTOCOCCUS NEOFORMANS
(2016-08)
Histidine-to-aspartate multi-step phosphorelay systems are used extensively by eukaryotes and bacteria to sense and respond to changes in their external environment and to control the regulation of crucial biological ...
Conformational dynamics and structure of FepA, a ligand-gated channel in the bacterial outer membrane.
(1998)
Since Waring & Werkman documented a microbial requirement for iron in 1944, much progress has been made in understanding how microbes assimilate this mundane but biological precious metal. The proteins involved in iron ...
Purification, Mechanism, and Biochemical Interactions of the Essential Mycolic Acid Transporters MmpL3 from Mycobacterium tuberculosis, and CmpL1 from Corynebacterium glutamicum.
(2020-06)
The Corynebacterium – Mycobacterium – Nocardia family (CMN family) are a subset group of actinomycetes which are characterized as acid-fast, Gram-positive species. Many members of the CMN family are causative agents of ...
A Computational Study of Amyloid Fibrils and their Structural Properties
(2017-12)
The term amyloid describes misfolded protein aggregates in which a highly ordered cross β-sheet pattern is adopted. While there exist functional amyloids, the majority of known amyloids are associated with diseases in ...