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Now showing items 11-20 of 20
Establishing Three-Dimensional Super-Resolution Microscopy Methods For Quantifying Intracellular Nanoparticle Distribution
(2023-12-15)
The systemic administration of nanomedicine formulations has been described as a promising treatment option for solid tumors at both preclinical and clinical stages. However, these treatments are currently limited to ...
Development of Contrast Agents for Optoacoustic Imaging
(2023-12-15)
Optoacoustic imaging is an emerging modality with inherent advantages relevant for clinical use. Following excitation of optoacoustic contrast agents with ultrashort (~10 ns) pulses of near-infrared light, thermoelastic ...
Developing Novel Computer Aided Diagnosis Schemes for Improved Classification of Mammography Detected Masses
(2023-12-15)
Mammography imaging is a population-based breast cancer screening tool that has greatly aided in the decrease in breast cancer mortality over time. Although mammography is the most frequently employed breast imaging modality, ...
Neuroimaging biomarkers for noninvasive brain stimulation in Mal de Débarquement syndrome
(2021-08-05)
This dissertation summarizes my work to identify biomarkers for neuromodulation treatment in Mal de Débarquement Syndrome (MdDS) using resting state EEG and fMRI. Biomarkers that are associated with the symptom changes ...
Peptide Aggregation Induced Immunogenic Cell Death
(2022-12-16)
Cell death is an inevitable biological outcome, every living thing dies. However, how cells die is an important question and ultimately is decisive in homeostasis and disease progression. Immune system is in the center of ...
Mapping brain activity and resting-state functional connectivity with functional near-infrared spectroscopy
(2022-08-04)
Functional near-infrared spectroscopy (fNIRS) as a non-invasive optical imaging technique to measure cerebral hemodynamics has seen rapid development and increasing use in studying the human brain. fNIRS measures relative ...
Translation and Development of Novel Annexin A5 - Protein Drug Conjugates for the Treatment of Triple-Negative Breast Cancer
(2022-12-16)
Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subset with limited targeted chemotherapies. TNBC is defined by the absence of the estrogen, progesterone, and HER2 hormonal receptors on the cell ...
Development of a Conductive Bioink Hydrogel for Translational Spinal Cord Regeneration
(2020-07-30)
Spinal cord injury (SCI) patients rarely recover full functionality with current clinical treatments. There are two approaches for developing treatments for SCI: 1) rehabilitation strategies and 2) regenerative medicine ...
Synthetic chondroinductive biomaterial for hyaline cartilage regeneration
(2024-05-10)
Avascularity, low cell count, and low proliferative potential constitute the triad that defines the limited self-regenerative potential of articular cartilage. Consequently, the repair of articular cartilage defects presents ...
Forward-view Endoscopic Optical Coherence Tomography for Needle-based Interventions
(2024-05-10)
During my five-year Ph.D. academic career at the University of Oklahoma, I would first express my deepest gratitude to Dr. Qinggong Tang. I really appreciate your assistance with both my research studies and daily life. ...