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Structural study of Parkinson's disease related protein LRRK2 and vaccinia virus protein A6
(2014-07)
LRRK2 is a multi-domain protein expressed widely in organs. The mutations of LRRK2 are related to Parkinson's disease. The Roc domain in LRRK2 is a Ras GTPase, and its GTP hydrolysis activity has been proved to regulate ...
Analysis of Coxiella burnetii mediated modulation of host cells during infection
(2011-07)
Scope and Method of Study: Scope - To determine Coxiella burnetii mediated modulation of host cell during infection. Methods for microbiological and molecular analyses include: eukaryotic and prokaryotic cell culture, ...
Characterization of internalization, recycling and downregulation of muscarinic receptors
(2011-12)
Scope and Method of Study: Muscarinic receptors mediate the responses elicited to the activation of the parasympathetic nervous system. Specifically, muscarinic receptors mediate exocrine glandular secretion, smooth muscle ...