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ApoA-I Induced Lipid Efflux from AdipocytesApoA-I induced lipid efflux from adipocytes
(2010-05)
Findings and Conclusions:
Virus detection in a metagenomic sequence dataset: Methods and applications
(2013-07)
Global trade of plant material has increased the introduction of foreign plant viruses in nations across the world. This has led to the need for increased abilities to detect plant viruses. Surveys assessing the viral ...
Dynein adaptor, Lis1/Pac1, is a sumoylation and ubiquitin substrate
(2015-05)
Microtubules are proteinaceous that contribute to cell motility and cell division. Microtubules are highly dynamic, continuously growing and shrinking. Because microtubules are fundamental for cell division, it is important ...
Proteomics fingerprints of AUY922 and 17-DMAG indicate common mechanisms of action for Hsp90 inhibitors
(2013-12)
In this work, we identified the proteomics fingerprint of the anti-cancer drug candidate AUY922 in Jurkat leukemia cells and compared AUY922's fingerprint to the proteomics fingerprints of flagship Hsp90 inhibitors 17-DMAG ...
Glycolysis and glyceroneogenesis in adipocytes: Effects of rosiglitazone, an anti-diabetic drug
(2010-07)
Findings and Conclusions:
Identification and characterization of natural compound inhibitors of the Hsp90 chaperone complex
(2013-07)
The 90 kDa Heat Shock Protein (Hsp90) has emerged as a major therapeutic target for a number of diseases, the most notable of which is cancer. Accordingly, many groups are attempting to develop small molecules that modulate ...
RNA-seq assisted gene modeling and annotation, transcriptome study and functional analysis of stress responsive peptides of Manduca sexta
(2016-12)
Manduca sexta is a widely used model insect. The genome sequence was determined using 454 sequencing technology, and Official Gene Set (OGS) 2.0 was generated with help from RNA-seq data and manually annotation by researchers ...
Functional modulation of DBC2 by the Hsp90 chaperone machine
(2012-05)
Scope and Method of Study: This study involved looking at various mechanistic associations of the tumor suppressor DBC2 with the Hsp90 chaperone machine. Along with aspects of functional relationships of co-chaperone and ...
ABFs and CBFs in cotton (Gossypium hirsutum): A characterization and functional analysis in response to abiotic stress
(2015-12)
Abiotic stress is pernicious; every year causing substantial reductions in agricultural yield. Despite this, due to the complex nature of the plant response, our current understanding of the molecular mechanisms and signaling ...