Browsing OU - Faculty and Staff Publications by Subject "Open-Access"
Now showing items 21-40 of 47
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Immunodominance of Antigenic Site B over Site A of Hemagglutinin of Recent H3N2 Influenza Viruses
(PLos One, 2012-07-25)H3N2 influenza viruses have now circulated in the human population for 43 years since the pandemic of 1968, accumulating sequence changes in the hemagglutinin (HA) and neuraminidase (NA) that are believed to be predominantly ... -
Improving Risk Models for Avian Influenza: The Role of Intensive Poultry Farming and Flooded Land during the 2004 Thailand Epidemic
(PLos One, 2012-11-19)Since 1996 when Highly Pathogenic Avian Influenza type H5N1 first emerged in southern China, numerous studies sought risk factors and produced risk maps based on environmental and anthropogenic predictors. However little ... -
Insights from Characterizing Extinct Human Gut Microbiomes
(PLos One, 2012-12-12)In an effort to better understand the ancestral state of the human distal gut microbiome, we examine feces retrieved from archaeological contexts (coprolites). To accomplish this, we pyrosequenced the 16S rDNA V3 region ... -
Isozyme-Specific Ligands for O-acetylserine sulfhydrylase, a Novel Antibiotic Target
(PLos One, 2013-10-22)The last step of cysteine biosynthesis in bacteria and plants is catalyzed by O-acetylserine sulfhydrylase. In bacteria, two isozymes, O-acetylserine sulfhydrylase-A and O-acetylserine sulfhydrylase-B, have been identified ... -
Mannose-Binding Lectin 2 Gene and Risk of Adult Glioma
(PLos One, 2013-04-18)Background and AimsThe immune system is likely to play a key role in the etiology of gliomas. Genetic polymorphisms in the mannose-binding lectin gene, a key activator in the lectin complement pathway, have been associated ... -
Metapopulation Dynamics Enable Persistence of Influenza A, Including A/H5N1, in Poultry
(PLos One, 2013-12-02)Highly pathogenic influenza A/H5N1 has persistently but sporadically caused human illness and death since 1997. Yet it is still unclear how this pathogen is able to persist globally. While wild birds seem to be a genetic ... -
Microbial Community Analysis of a Coastal Salt Marsh Affected by the Deepwater Horizon Oil Spill
(PLos One, 2012-07-18)Coastal salt marshes are highly sensitive wetland ecosystems that can sustain long-term impacts from anthropogenic events such as oil spills. In this study, we examined the microbial communities of a Gulf of Mexico coastal ... -
Microbial Electricity Generation Enhances Decabromodiphenyl Ether (BDE-209) Degradation
(PLos One, 2013-08-05)Due to environmental persistence and biotoxicity of polybrominated diphenyl ethers (PBDEs), it is urgent to develop potential technologies to remediate PBDEs. Introducing electrodes for microbial electricity generation to ... -
NUCLEAR FACTOR Y Transcription Factors Have Both Opposing and Additive Roles in ABA-Mediated Seed Germination
(PLos One, 2013-03-19)In the model organism Arabidopsis thaliana the heterotrimeric transcription factor NUCLEAR FACTOR Y (NF-Y) has been shown to play multiple roles in facilitating plant growth and development. Although NF-Y itself represents ... -
Nutritional Basis for Colonization Resistance by Human Commensal Escherichia coli Strains HS and Nissle 1917 against E. coli O157:H7 in the Mouse Intestine
(PLos One, 2013-01-17)Escherichia coli is a single species consisting of many biotypes, some of which are commensal colonizers of mammals and others that cause disease. Humans are colonized on average with five commensal biotypes, and it is ... -
The Ontogenetic Osteohistology of Tenontosaurus tilletti
(PLos One, 2012-03-28)Tenontosaurus tilletti is an ornithopod dinosaur known from the Early Cretaceous (Aptian-Albian) Cloverly and Antlers formations of the Western United States. It is represented by a large number of specimens spanning a ... -
Phylotyping and Functional Analysis of Two Ancient Human Microbiomes
(PLos One, 2008-11-11)BackgroundThe Human Microbiome Project (HMP) is one of the U.S. National Institutes of Health Roadmap for Medical Research. Primary interests of the HMP include the distinctiveness of different gut microbiomes, the factors ... -
Physiological Roles of ArcA, Crp, and EtrA and Their Interactive Control on Aerobic and Anaerobic Respiration in Shewanella oneidensis
(PLos One, 2010-12-28)In the genome of Shewanella oneidensis, genes encoding the global regulators ArcA, Crp, and EtrA have been identified. All these proteins deviate from their counterparts in E. coli significantly in terms of functionality ... -
Prefrontal Control of the Amygdala during Real-Time fMRI Neurofeedback Training of Emotion Regulation
(PLos One, 2013-11-06)We observed in a previous study (PLoS ONE 6:e24522) that the self-regulation of amygdala activity via real-time fMRI neurofeedback (rtfMRI-nf) with positive emotion induction was associated, in healthy participants, with ... -
Psychedelics and the Human Receptorome
(PLos One, 2010-02-02)We currently understand the mental effects of psychedelics to be caused by agonism or partial agonism of 5-HT2A (and possibly 5-HT2C) receptors, and we understand that psychedelic drugs, especially phenylalkylamines, are ... -
Purine Nucleoside Phosphorylase Targeted by Annexin V to Breast Cancer Vasculature for Enzyme Prodrug Therapy
(PLos One, 2013-10-03)Background and PurposeThe targeting of therapeutics is a promising approach for the development of new cancer treatments that seek to reduce the devastating side effects caused by the systemic administration of current ... -
Role of Catecholate Siderophores in Gram-Negative Bacterial Colonization of the Mouse Gut
(PLos One, 2012-11-29)We investigated the importance of the production of catecholate siderophores, and the utilization of their iron (III) complexes, to colonization of the mouse intestinal tract by Escherichia coli. First, a ΔtonB strain was ... -
Self-Renewal and Differentiation Capacity of Urine-Derived Stem Cells after Urine Preservation for 24 Hours
(PLos One, 2013-01-18)Despite successful approaches to preserve organs, tissues, and isolated cells, the maintenance of stem cell viability and function in body fluids during storage for cell distribution and transportation remains unexplored. ... -
Shared and Unique Patterns of Embryo Development in Extremophile Poeciliids
(PLos One, 2011-11-07)Background Closely related lineages of livebearing fishes have independently adapted to two extreme environmental factors: toxic hydrogen sulphide (H2S) and perpetual darkness. Previous work has demonstrated in ... -
Similar Gene Estimates from Circular and Linear Standards in Quantitative PCR Analyses Using the Prokaryotic 16S rRNA Gene as a Model
(PLos One, 2012-12-19)Quantitative PCR (qPCR) is one of the most widely used tools for quantifying absolute numbers of microbial gene copies in test samples. A recent publication showed that circular plasmid DNA standards grossly overestimated ...