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Now showing items 21-30 of 35
NMR studies of membrane proteins
(Springer Nature, 2010-01-01)
Nuclear magnetic resonance studies of membrane proteins yield valuable insights into their structure and topology. For example, the tilt angle and rotation of the helices in an ion channel can be determined by solid-state ...
Deep sequencing of small RNA libraries reveals dynamic regulation of conserved and novel microRNAs and microRNA-stars during silkworm development
(BioMed Central, 2010-01-20)
Background: In eukaryotes, microRNAs (miRNAs) have emerged as critical regulators of gene expression. The Silkworm (Bombyx mori L.) is one of the most suitable lepidopteran insects for studying the molecular aspects of ...
Conjugated polymer nanoparticles for effective siRNA delivery to tobacco BY-2 protoplasts
(BioMed Central, 2010-12-30)
Background: Post transcriptional gene silencing (PTGS) is a mechanism harnessed by plant biologists to knock down gene expression. siRNAs contribute to PTGS that are synthesized from mRNAs or viral RNAs and function to ...
Spatial distribution and risk factors of Brucellosis in Iberian wild ungulates
(BioMed Central, 2010-03-05)
Background: The role of wildlife as a brucellosis reservoir for humans and domestic livestock remains to be properly established. The aim of this work was to determine the aetiology, apparent prevalence, spatial distribution ...
Use of a rabbit soft tissue chamber model to investigate Campylobacter jejuni-host interactions
(Frontiers Media, 2010-11-16)
Despite the prevalence of Campylobacter jejuni as an important food borne pathogen, the microbial factors governing its infection process are poorly characterized. In this study, we developed a novel rabbit soft tissue ...
Coxiella burnetii Nine Mile II proteins modulate gene expression of monocytic host cells during infection
(BioMed Central, 2010-09-20)
Background: Coxiella burnetii is an intracellular bacterial pathogen that causes acute and chronic disease in humans. Bacterial replication occurs within enlarged parasitophorous vacuoles (PV) of eukaryotic cells, the ...
Environmental determinants of and impact on childhood asthma by the bacterial community in household dust
(American Society for Microbiology, 2010-04)
Asthma increased dramatically in the last decades of the 20th century and is representative of chronic diseases that have been linked to altered microbial exposure and immune responses. Here we evaluate the effects of ...
Differential expression of genes in salivary glands of male Rhipicephalus (Boophilus) microplus in response to infection with Anaplasma marginale
(BioMed Central, 2010-03-18)
Background: Bovine anaplasmosis, caused by the rickettsial tick-borne pathogen Anaplasma marginale (Rickettsiales: Anaplasmataceae), is vectored by Rhipicephalus (Boophilus)microplus in many tropical and subtropical regions ...
Ethyl 2-(3-acetyl-6-methyl-2-oxo-2H-pyran-4-yloxy)acetate
(International Union of Crystallography, 2010)
Rumen microbial population dynamics during adaptation to a high-grain diet
(American Society for Microbiology, 2010-11)
High-grain adaptation programs are widely used with feedlot cattle to balance enhanced growth performance against the risk of acidosis. This adaptation to a high-grain diet from a high-forage diet is known to change the ...