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Anaplasma phagocytophilum MSP4 and HSP70 proteins are involved in interactions with host cells during pathogen infection
(Frontiers Media, 2017-07-05)
Anaplasma phagocytophilum transmembrane and surface proteins play a role during infection and multiplication in host neutrophils and tick vector cells. Recently, A. phagocytophilum Major surface protein 4 (MSP4) and Heat ...
Interaction of the tick immune system with transmitted pathogens
(Frontiers Media, 2013-07-16)
Ticks are hematophagous arachnids transmitting a wide variety of pathogens including viruses, bacteria, and protozoans to their vertebrate hosts. The tick vector competence has to be intimately linked to the ability of ...
Vaccinomics approach to the identification of candidate protective antigens for the control of tick vector infestations and Anaplasma phagocytophilum infection
(Frontiers Media, 2017-08-09)
Anaplasma phagocytophilum is an emerging tick-borne pathogen causing human granulocytic anaplasmosis (HGA), tick-borne fever (TBF) in small ruminants, and other forms of anaplasmosis in different domestic and wild animals. ...
Impact of climate trends on tick-borne pathogen transmission
(Frontiers Media, 2012-03-27)
Recent advances in climate research together with a better understanding of tick-pathogen interactions, the distribution of ticks and the diagnosis of tick-borne pathogens raise questions about the impact of environmental ...
Tick-pathogen interactions and vector competence: Identification of molecular drivers for tick-borne diseases
(Frontiers Media, 2017-04-07)
Ticks and the pathogens they transmit constitute a growing burden for human and animal health worldwide. Vector competence is a component of vectorial capacity and depends on genetic determinants affecting the ability of ...
Subolesin expression in response to pathogen infection in ticks
(BioMed Central, 2010-02-19)
Background: Ticks (Acari: Ixodidae) are vectors of pathogens worldwide that cause diseases in humans and animals. Ticks and pathogens have co-evolved molecular mechanisms that contribute to their mutual development and ...
Evidence of the role of tick subolesin in gene expression
(BioMed Central, 2008-08-02)
Background: Subolesin is an evolutionary conserved protein that was discovered recently in Ixodes scapularis as a tick protective antigen and has a role in tick blood digestion, reproduction and development. In other ...
Tissue-specific signatures in the transcriptional response to Anaplasma phagocytophilum infection of Ixodes scapularis and Ixodes ricinus tick cell lines
(Frontiers Media, 2016-02-10)
Anaplasma phagocytophilum are transmitted by Ixodes spp. ticks and have become one of the most common and relevant tick-borne pathogens due to their impact on human and animal health. Recent results have increased our ...
Tick genome assembled: New opportunities for research on tick-host-pathogen interactions
(Frontiers Media, 2016-09-15)
As tick-borne diseases are on the rise, an international effort resulted in the sequence and assembly of the first genome of a tick vector. This result promotes research on comparative, functional and evolutionary genomics ...
Allopatric speciation in ticks: Genetic and reproductive divergence between geographic strains of Rhipicephalus (Boophilus) microplus
(BioMed Central, 2009-02-25)
Background: The cattle tick, Rhipicephalus (Boophilus) microplus, economically impact cattle industry in tropical and subtropical regions of the world. The morphological and genetic differences among R. microplus strains ...