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Mapping of schistosomiasis and soil-transmitted helminths in Namibia: The first large-scale protocol to formally include rapid diagnostic tests
(Public Library of Science (PLoS), 2015-07-21)
Background: Namibia is now ready to begin mass drug administration of praziquantel and albendazole against schistosomiasis and soil-transmitted helminths, respectively. Although historical data identifies areas of transmission ...
Low seroprevalence of antibodies to Toxoplasma gondii in blood donors in central Namibia
(Informa UK Limited, 2014)
Although emphasis has been placed on research relating to human immunodeficiency virus (HIV), tuberculosis and malaria, several researchers in Africa are focusing on other threats to human health, such as neglected tropical ...
Risk assessment of flavivirus transmission in Namibia
(Elsevier BV, 2014-05-25)
The role of arboviruses causing acute febrile illness in sub-Saharan Africa is receiving more attention. Reports of dengue in tourists were published nearly 10 years ago in Namibia, but the current epidemiology of arboviruses ...
Mycobacteria, metals, and the macrophage
(Wiley, 2015-03)
Mycobacterium tuberculosis is a facultative intracellular pathogen that thrives inside host macrophages. A key trait of M. tuberculosis is to exploit and manipulate metal cation trafficking inside infected macrophages to ...
Updated checklist of the mosquitoes of Oklahoma including new state records and West Nile virus vectors, 2003-06
(The American Mosquito Control Association, 2015-12)
The mosquito fauna of Oklahoma has not been evaluated since 1965 and no report has been published concerning species associated with urban areas in the state. Mosquito collections were conducted as part of the West Nile ...
Shiga toxin 2 overexpression in Escherichia coli O157:H7 strains associated with severe human disease
(Elsevier, 2011-12)
Variation in disease severity among Escherichia coli O157:H7 infections may result from differential expression of Shiga toxin 2 (Stx2). Eleven strains belonging to four prominent phylogenetic clades, including clade 8 ...
Neglected tropical diseases of Namibia: Unsolved mysteries
(Elsevier BV, 2012-09-21)
Neglected tropical diseases (NTDs) are diseases most commonly found in settings of poverty and are responsible for the morbidity and/or mortality of millions each year. As an upper-middle income country, Namibia is not ...
PPE surface proteins are required for heme utilization by Mycobacterium tuberculosis
(American Society for Microbiology, 2017-03-08)
Iron is essential for replication of Mycobacterium tuberculosis, but iron is efficiently sequestered in the human host during infection. Heme constitutes the largest iron reservoir in the human body and is utilized by many ...
Exposure and risk factors to Coxiella burnetii, spotted fever group and typhus group rickettsiae, and Bartonella henselae among volunteer blood donors in Namibia
(Public Library of Science (PLoS), 2014-09-26)
Background: The role of pathogen-mediated febrile illness in sub-Saharan Africa is receiving more attention, especially in Southern Africa where four countries (including Namibia) are actively working to eliminate malaria. ...
Development of a loop-mediated isothermal amplification (LAMP) assay for rapid screening of ticks and fleas for spotted fever group rickettsia
(Public Library of Science (PLoS), 2018-02-01)
Background: The importance of tick and flea-borne rickettsia infections is increasingly recognized worldwide. While increased focus has shifted in recent years to the development of point-of-care diagnostics for various ...