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Sensitivity of monkey B virus (Cercopithecine herpesvirus 1) to antiviral drugs: Role of thymidine kinase in antiviral activities of substrate analogs and acyclonucleosides
(American Society for Microbiology, 2007-06)
Herpes B virus (B virus [BV]) is a macaque herpesvirus that is occasionally transmitted to humans where it can cause rapidly ascending encephalitis that is often fatal. To understand the low susceptibility of BV to the ...
New Mycobacterium avium antifolate shows synergistic effect when used in combination with dihydropteroate synthase inhibitors
(American Society for Microbiology, 2005-11)
Mycobacterium avium complex (MAC) is resistant to trimethoprim, an inhibitor of bacterial dihydrofolate reductase (DHFR). A previously identified selective inhibitor of MAC DHFR, SRI-8858, was shown to have synergistic ...