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Single-fiber reflectance spectroscopy of isotropic-scattering medium: An analytic perspective to the ratio-of-remission in steady-state measurements
(MDPI, 2014-12-16)
Recent focused Monte Carlo and experimental studies on steady-state single-fiber reflectance spectroscopy (SfRS) from a biologically relevant scattering medium have revealed that, as the dimensionless reduced scattering ...
In vivo percutaneous reflectance spectroscopy of fatty liver development in rats suggests that the elevation of the scattering power is an early indicator of hepatic steatosis
(World Scientific Publishing, 2018-05-11)
This study assessed whether there was a scattering spectral marker quantifiable by reflectance measurements that could indicate early development of hepatic steatosis in rats for potential applications to pre-procurement ...
On the geometry dependence of differential pathlength factor for near-infrared spectroscopy. I. Steady-state with homogeneous medium
(SPIE, the international society for optics and photonics, 2015-10-14)
This work analytically examines some dependences of the differential pathlength factor (DPF) for steady-state photon diffusion in a homogeneous medium on the shape, dimension, and absorption and reduced scattering coefficients ...
Perspective review on solid-organ transplant: Needs in point-of-care optical biomarkers
(SPIE, the international society for optics and photonics, 2018-08-29)
Solid-organ transplant is one of the most complex areas of modern medicine involving surgery. There are challenging opportunities in solid-organ transplant, specifically regarding the deficiencies in pathology workflow or ...
Flexible nine-channel photodetector probe facilitated intraspinal multisite transcutaneous photobiomodulation therapy dosimetry in cadaver dogs
(SPIE, the international society for optics and photonics, 2018-01-23)
Noninvasive photobiomodulation therapy (PBMT) of spinal cord disease remains speculative due to the lack of evidence for whether photobiomodulatory irradiances can be transcutaneously delivered to the spinal cord under a ...
Toward transduodenal diffuse optical tomography of proximal pancreas
(Optica Publishing Group, 2013-10-10)
We demonstrate the feasibility of diffuse optical tomography (DOT) of the proximal pancreas by using optical applicator channels deployed longitudinally along the exterior surface of a duodenoscope. As the duodenum that ...
Effects of capsule on surface diffuse reflectance spectroscopy of the subcapsular parenchyma of a solid organ
(SPIE, the international society for optics and photonics, 2018-07-27)
We hypothesize that the capsular optical properties and thickness combined affect how accurate the diffuse reflectance on the surface of a capsular solid organ represents that on the subcapsular parenchyma. Monte Carlo ...
Freehand diffuse optical spectroscopy imaging for intraoperative identification of major venous and arterial vessels underlying peritoneal fat: An in vivo demonstration in a pig model
(SPIE, the international society for optics and photonics, 2017-10-30)
Inadvertent injury to important anatomic structures is a significant risk in minimally invasive surgery (MIS) that potentially requires conversion to an open procedure, which results in increased morbidity and mortality. ...
Self calibration iso-pathlength point in cylindrical tissue geometry: Solution of steady-state photon diffusion based on the extrapolated zero-boundary
(Optica Publishing Group, 2018-12-21)
Near-infrared optical techniques permit tissue diagnosis by surface measurement. However, the geometrical shape of this interface profiles the intensity of the surface measurement, which is found to have an iso-pathlength ...
In vivo assessment of diet-induced rat hepatic steatosis development by percutaneous single-fiber spectroscopy detects scattering spectral changes due to fatty infiltration
(SPIE, the international society for optics and photonics, 2015-11-05)
This study explores percutaneous single-fiber spectroscopy (SfS) of rat livers undergoing fatty infiltration. Eight test rats were fed a methionine-choline-deficient (MCD) diet, and four control rats were fed a normal diet. ...