Self calibration iso-pathlength point in cylindrical tissue geometry: Solution of steady-state photon diffusion based on the extrapolated zero-boundary
Abstract
Near-infrared optical techniques permit tissue diagnosis by surface measurement. However, the geometrical shape of this interface profiles the intensity of the surface measurement, which is found to have an iso-pathlength (IPL) point allowing for absorption identification independent of tissue scattering. The IPL point was projected in Monte Carlo (MC) simulation, validated experimentally in cylindrical tissues, but remains under-appreciated through analytical approaches. In this work, we present an analytical solution of an IPL point for steady-state diffusion based on the extrapolated zero-boundary condition. The same IPL points were found when comparing this solution to 3-D MC simulations for a tissue radius range of 5-8mm.
Citation
Duadi, H., Piao, D., Fixler, D. (2018). Self calibration iso-pathlength point in cylindrical tissue geometry: Solution of steady-state photon diffusion based on the extrapolated zero-boundary. OSA Continuum, 2(1), 92-98. https://doi.org/10.1364/OSAC.2.000092