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Portable near-infrared diffusive light imager for breast cancer detection
(SPIE, the international society for optics and photonics, 2004-02-03)
We present a frequency-domain near-infrared optical tomography system designed for breast cancer detection, in conjunction, with conventional ultrasound. It features fast optical switching, threewavelength excitations, and ...
On the geometry dependence of differential pathlength factor for near-infrared spectroscopy. I. Steady-state with homogeneous medium
(SPIE, the international society for optics and photonics, 2015-10-14)
This work analytically examines some dependences of the differential pathlength factor (DPF) for steady-state photon diffusion in a homogeneous medium on the shape, dimension, and absorption and reduced scattering coefficients ...
Trans-rectal ultrasound-coupled near-infrared optical tomography of the prostate. Part II: Experimental demonstration
(Optica Publishing Group, 2008-10-15)
We demonstrate trans-rectal optical tomography of the prostate using an endo-rectal near-infrared (NIR) applicator integrated with a transrectal ultrasound (TRUS) probe. The endo-rectal NIR applicator incorporated a design ...
Perspective review on solid-organ transplant: Needs in point-of-care optical biomarkers
(SPIE, the international society for optics and photonics, 2018-08-29)
Solid-organ transplant is one of the most complex areas of modern medicine involving surgery. There are challenging opportunities in solid-organ transplant, specifically regarding the deficiencies in pathology workflow or ...
Trans-rectal ultrasound-coupled near-infrared optical tomography of the prostate. Part I: Simulation
(Optica Publishing Group, 2008-10-15)
We investigate the feasibility of trans-rectal optical tomography of the prostate using an endo-rectal near-infrared (NIR) applicator that is to be integrated with a trans-rectal ultrasound (TRUS) probe. Integration with ...
Flexible nine-channel photodetector probe facilitated intraspinal multisite transcutaneous photobiomodulation therapy dosimetry in cadaver dogs
(SPIE, the international society for optics and photonics, 2018-01-23)
Noninvasive photobiomodulation therapy (PBMT) of spinal cord disease remains speculative due to the lack of evidence for whether photobiomodulatory irradiances can be transcutaneously delivered to the spinal cord under a ...
Toward transduodenal diffuse optical tomography of proximal pancreas
(Optica Publishing Group, 2013-10-10)
We demonstrate the feasibility of diffuse optical tomography (DOT) of the proximal pancreas by using optical applicator channels deployed longitudinally along the exterior surface of a duodenoscope. As the duodenum that ...
In vivo trans-rectal ultrasound-coupled optical tomography of a transmissible venereal tumor model in the canine pelvic canal
(SPIE, the international society for optics and photonics, 2009-05-01)
In vivo trans-rectal near-infrared (NIR) optical tomography was performed concurrently with, albeit reconstructed without spatial a prior of, trans-rectal ultrasound (US) on transmissible venereal tumor (TVT) developed as ...
Hybrid positron detection and optical coherence tomography system: Design, calibration, and experimental validation with rabbit atherosclerotic models
(SPIE, the international society for optics and photonics, 2005-07-01)
We evaluate the performance of our novel hybrid optical coherence tomography (OCT) and scintillating probe, demonstrate simultaneous OCT imaging and scintillating detection, and validate the system using an atherosclerotic ...
Effects of capsule on surface diffuse reflectance spectroscopy of the subcapsular parenchyma of a solid organ
(SPIE, the international society for optics and photonics, 2018-07-27)
We hypothesize that the capsular optical properties and thickness combined affect how accurate the diffuse reflectance on the surface of a capsular solid organ represents that on the subcapsular parenchyma. Monte Carlo ...