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Single-fiber reflectance spectroscopy of isotropic-scattering medium: An analytic perspective to the ratio-of-remission in steady-state measurements
(MDPI, 2014-12-16)
Recent focused Monte Carlo and experimental studies on steady-state single-fiber reflectance spectroscopy (SfRS) from a biologically relevant scattering medium have revealed that, as the dimensionless reduced scattering ...
Diffuse optical tomography to monitor the photocoagulation front during interstitial photothermal therapy: Numerical simulations and measurements in tissue-simulating phantoms
(De Gruyter, 2014-08-06)
Near-infrared interstitial photothermal therapy (PTT) is currently undergoing clinical trials as an alternative to watchful waiting or radical treatments in patients with low/intermediate-risk focal prostate cancer. ...
In vivo percutaneous reflectance spectroscopy of fatty liver development in rats suggests that the elevation of the scattering power is an early indicator of hepatic steatosis
(World Scientific Publishing, 2018-05-11)
This study assessed whether there was a scattering spectral marker quantifiable by reflectance measurements that could indicate early development of hepatic steatosis in rats for potential applications to pre-procurement ...
The utility of direct-current as compared to frequency domain measurements in spectrally-constrained diffuse optical tomography toward cancer imaging
(SAGE Publications, 2011-10-01)
This work investigates, by means of analytical and simulation studies, the performance of spectrally-constrained image reconstruction in Continuous-Wave or Direct-Current (DC) and Frequency Domain (FD) near-infrared optical ...
Trans-rectal ultrasound-coupled near-infrared optical tomography of the prostate. Part II: Experimental demonstration
(Optica Publishing Group, 2008-10-15)
We demonstrate trans-rectal optical tomography of the prostate using an endo-rectal near-infrared (NIR) applicator integrated with a transrectal ultrasound (TRUS) probe. The endo-rectal NIR applicator incorporated a design ...
Trans-rectal ultrasound-coupled near-infrared optical tomography of the prostate. Part I: Simulation
(Optica Publishing Group, 2008-10-15)
We investigate the feasibility of trans-rectal optical tomography of the prostate using an endo-rectal near-infrared (NIR) applicator that is to be integrated with a trans-rectal ultrasound (TRUS) probe. Integration with ...
Hybrid positron detection and optical coherence tomography system: Design, calibration, and experimental validation with rabbit atherosclerotic models
(SPIE, the international society for optics and photonics, 2005-07-01)
We evaluate the performance of our novel hybrid optical coherence tomography (OCT) and scintillating probe, demonstrate simultaneous OCT imaging and scintillating detection, and validate the system using an atherosclerotic ...
Transrectal ultrasound-integrated spectral optical tomography of hypoxic progression of a regressing tumor in a canine prostate
(SAGE Publications, 2011-12-01)
The objective of this study was to evaluate if transrectal optical tomography implemented at three wavelength bands for spectral detection could monitor changes of the hemoglobin oxygen saturation (SₜO₂) in addition to ...
Freehand diffuse optical spectroscopy imaging for intraoperative identification of major venous and arterial vessels underlying peritoneal fat: An in vivo demonstration in a pig model
(SPIE, the international society for optics and photonics, 2017-10-30)
Inadvertent injury to important anatomic structures is a significant risk in minimally invasive surgery (MIS) that potentially requires conversion to an open procedure, which results in increased morbidity and mortality. ...