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In vivo percutaneous reflectance spectroscopy of fatty liver development in rats suggests that the elevation of the scattering power is an early indicator of hepatic steatosis
(World Scientific Publishing, 2018-05-11)
This study assessed whether there was a scattering spectral marker quantifiable by reflectance measurements that could indicate early development of hepatic steatosis in rats for potential applications to pre-procurement ...
Portable near-infrared diffusive light imager for breast cancer detection
(SPIE, the international society for optics and photonics, 2004-02-03)
We present a frequency-domain near-infrared optical tomography system designed for breast cancer detection, in conjunction, with conventional ultrasound. It features fast optical switching, threewavelength excitations, and ...
On the geometry dependence of differential pathlength factor for near-infrared spectroscopy. I. Steady-state with homogeneous medium
(SPIE, the international society for optics and photonics, 2015-10-14)
This work analytically examines some dependences of the differential pathlength factor (DPF) for steady-state photon diffusion in a homogeneous medium on the shape, dimension, and absorption and reduced scattering coefficients ...
Trans-rectal ultrasound-coupled near-infrared optical tomography of the prostate. Part II: Experimental demonstration
(Optica Publishing Group, 2008-10-15)
We demonstrate trans-rectal optical tomography of the prostate using an endo-rectal near-infrared (NIR) applicator integrated with a transrectal ultrasound (TRUS) probe. The endo-rectal NIR applicator incorporated a design ...
Towards non-contact glucose sensing in aqueous turbid medium at ∼1.1 meters distance
(Institute of Electrical and Electronics Engineers (IEEE), 2020-07-30)
This work demonstrates a non-contact diffuse reflectance approach with a working distance of ∼1.1 meters for the potential of glucose sensing. Non-contact diffuse reflectance over 1.1-1.3 μm was developed according to a ...
Perspective review on solid-organ transplant: Needs in point-of-care optical biomarkers
(SPIE, the international society for optics and photonics, 2018-08-29)
Solid-organ transplant is one of the most complex areas of modern medicine involving surgery. There are challenging opportunities in solid-organ transplant, specifically regarding the deficiencies in pathology workflow or ...
Trans-rectal ultrasound-coupled near-infrared optical tomography of the prostate. Part I: Simulation
(Optica Publishing Group, 2008-10-15)
We investigate the feasibility of trans-rectal optical tomography of the prostate using an endo-rectal near-infrared (NIR) applicator that is to be integrated with a trans-rectal ultrasound (TRUS) probe. Integration with ...
Flexible nine-channel photodetector probe facilitated intraspinal multisite transcutaneous photobiomodulation therapy dosimetry in cadaver dogs
(SPIE, the international society for optics and photonics, 2018-01-23)
Noninvasive photobiomodulation therapy (PBMT) of spinal cord disease remains speculative due to the lack of evidence for whether photobiomodulatory irradiances can be transcutaneously delivered to the spinal cord under a ...
Toward transduodenal diffuse optical tomography of proximal pancreas
(Optica Publishing Group, 2013-10-10)
We demonstrate the feasibility of diffuse optical tomography (DOT) of the proximal pancreas by using optical applicator channels deployed longitudinally along the exterior surface of a duodenoscope. As the duodenum that ...
In vivo trans-rectal ultrasound-coupled optical tomography of a transmissible venereal tumor model in the canine pelvic canal
(SPIE, the international society for optics and photonics, 2009-05-01)
In vivo trans-rectal near-infrared (NIR) optical tomography was performed concurrently with, albeit reconstructed without spatial a prior of, trans-rectal ultrasound (US) on transmissible venereal tumor (TVT) developed as ...