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Now showing items 21-29 of 29
A low-cost needle-based single-fiber reflectance spectroscopy method to probe scattering changes associated with mineralization in intervertebral discs in chondrodystrophoid canine species - A pilot study
(De Gruyter, 2012-05-01)
Background and objectives: Intervertebral disc herniation is a common disease in chondrodystrophic dogs, and a similar neurologic condition also occurs in humans. Percutaneous laser disc ablation (PLDA) is a minimally ...
Hybrid positron detection and optical coherence tomography system: Design, calibration, and experimental validation with rabbit atherosclerotic models
(SPIE, the international society for optics and photonics, 2005-07-01)
We evaluate the performance of our novel hybrid optical coherence tomography (OCT) and scintillating probe, demonstrate simultaneous OCT imaging and scintillating detection, and validate the system using an atherosclerotic ...
Effects of capsule on surface diffuse reflectance spectroscopy of the subcapsular parenchyma of a solid organ
(SPIE, the international society for optics and photonics, 2018-07-27)
We hypothesize that the capsular optical properties and thickness combined affect how accurate the diffuse reflectance on the surface of a capsular solid organ represents that on the subcapsular parenchyma. Monte Carlo ...
Transrectal ultrasound-integrated spectral optical tomography of hypoxic progression of a regressing tumor in a canine prostate
(SAGE Publications, 2011-12-01)
The objective of this study was to evaluate if transrectal optical tomography implemented at three wavelength bands for spectral detection could monitor changes of the hemoglobin oxygen saturation (SₜO₂) in addition to ...
Freehand diffuse optical spectroscopy imaging for intraoperative identification of major venous and arterial vessels underlying peritoneal fat: An in vivo demonstration in a pig model
(SPIE, the international society for optics and photonics, 2017-10-30)
Inadvertent injury to important anatomic structures is a significant risk in minimally invasive surgery (MIS) that potentially requires conversion to an open procedure, which results in increased morbidity and mortality. ...
Self calibration iso-pathlength point in cylindrical tissue geometry: Solution of steady-state photon diffusion based on the extrapolated zero-boundary
(Optica Publishing Group, 2018-12-21)
Near-infrared optical techniques permit tissue diagnosis by surface measurement. However, the geometrical shape of this interface profiles the intensity of the surface measurement, which is found to have an iso-pathlength ...
In vivo trans-rectal ultrasound-coupled near-infrared optical tomography of intact normal canine prostate
(World Scientific Publishing, 2009-07-01)
This is the first tomography-presentation of the optical properties of a normal canine prostate, in vivo, in its native intact environment in the pelvic canal. The imaging was performed by trans-rectal near-infrared (NIR) ...
Digital signal processor-based real-time optical Doppler tomography system
(SPIE, the international society for optics and photonics, 2004-05-01)
We present a real-time data-processing and display unit, based on a custom-designed digital signal processor (DSP) module for imaging tissue structure and Doppler blood flow. The DSP module is incorporated into a conventional ...
In vivo assessment of diet-induced rat hepatic steatosis development by percutaneous single-fiber spectroscopy detects scattering spectral changes due to fatty infiltration
(SPIE, the international society for optics and photonics, 2015-11-05)
This study explores percutaneous single-fiber spectroscopy (SfS) of rat livers undergoing fatty infiltration. Eight test rats were fed a methionine-choline-deficient (MCD) diet, and four control rats were fed a normal diet. ...