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Shiga toxin 2 overexpression in Escherichia coli O157:H7 strains associated with severe human disease
(Elsevier, 2011-12)
Variation in disease severity among Escherichia coli O157:H7 infections may result from differential expression of Shiga toxin 2 (Stx2). Eleven strains belonging to four prominent phylogenetic clades, including clade 8 ...
Neglected tropical diseases of Namibia: Unsolved mysteries
(Elsevier BV, 2012-09-21)
Neglected tropical diseases (NTDs) are diseases most commonly found in settings of poverty and are responsible for the morbidity and/or mortality of millions each year. As an upper-middle income country, Namibia is not ...
Role for zinc transporter gene SLC39A12 in the nervous system and beyond
(Elsevier, 2021-10-05)
The SLC39A12 gene encodes the zinc transporter protein ZIP12, which is expressed across many tissues and is highly abundant in the vertebrate nervous system. As a zinc transporter, ZIP12 functions to transport zinc across ...
Exposure and risk factors to Coxiella burnetii, spotted fever group and typhus group rickettsiae, and Bartonella henselae among volunteer blood donors in Namibia
(Public Library of Science (PLoS), 2014-09-26)
Background: The role of pathogen-mediated febrile illness in sub-Saharan Africa is receiving more attention, especially in Southern Africa where four countries (including Namibia) are actively working to eliminate malaria. ...
Mosquito-borne parasites in the Great Plains: Searching for vectors of nematodes and avian malaria parasites
(Elsevier BV, 2021)
Vector-borne diseases in the United States have recently increased as a result of the changing nature of vectors, hosts, reservoirs, parasite/pathogens, and the ecological and environmental conditions. While most focus has ...
Mosquito ingestion of antibodies against mosquito midgut microbiota improves conversion of ookinetes to oocysts for Plasmodium falciparum, but not P. yoelii
(Elsevier BV, 2011-07-13)
The mosquito midgut is a site of complex interactions between the mosquito, the malaria parasite and the resident bacterial flora. In laboratory experiments, we observed significant enhancement of Plasmodium falciparum ...