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Mapping of schistosomiasis and soil-transmitted helminths in Namibia: The first large-scale protocol to formally include rapid diagnostic tests
(Public Library of Science (PLoS), 2015-07-21)
Background: Namibia is now ready to begin mass drug administration of praziquantel and albendazole against schistosomiasis and soil-transmitted helminths, respectively. Although historical data identifies areas of transmission ...
Sigma factor n, liaison to an ntrC and rpoS dependent regulatory pathway controlling acid resistance and the LEE in enterohemorrhagic Escherichia coli
(Public Library of Science (PLoS), 2012)
Enterohemorrhagic Escherichia coli (EHEC) is dependent on acid resistance for gastric passage and low oral infectious dose, and the locus of enterocyte effacement (LEE) for intestinal colonization. Mutation of rpoN, encoding ...
Risk assessment of flavivirus transmission in Namibia
(Elsevier BV, 2014-05-25)
The role of arboviruses causing acute febrile illness in sub-Saharan Africa is receiving more attention. Reports of dengue in tourists were published nearly 10 years ago in Namibia, but the current epidemiology of arboviruses ...
High prevalence of "Candidatus Rickettsia andeanae" and apparent exclusion of Rickettsia parkeri in adult Amblyomma maculatum (Acari: Ixodidae) from Kansas and Oklahoma
(Elsevier BV, 2015-03-13)
Amblyomma maculatum (the Gulf Coast tick), an aggressive, human-biting, Nearctic and Neotropical tick, is the principal vector of Rickettsia parkeri in the United States. This pathogenic spotted fever group Rickettsia ...
Exogenously scavenged and endogenously synthesized heme are differentially utilized by Mycobacterium tuberculosis
(American Society for Microbiology, 2022-10-26)
Heme is both an essential cofactor and an abundant source of nutritional iron for the human pathogen Mycobacterium tuberculosis. While heme is required for M. tuberculosis survival and virulence, it is also potentially ...
Risk of encountering ticks and tick-borne pathogens in a rapidly growing metropolitan area in the U.S. Great Plains
(Elsevier BV, 2016-10-14)
The prevalence of tick-borne diseases has increased dramatically in many urban areas of the U.S., yet little is known about the ecology of ticks and tick-borne pathogens in relation to characteristics of North American ...
Mycobacteria, metals, and the macrophage
(Wiley, 2015-03)
Mycobacterium tuberculosis is a facultative intracellular pathogen that thrives inside host macrophages. A key trait of M. tuberculosis is to exploit and manipulate metal cation trafficking inside infected macrophages to ...
Invasive plants as foci of mosquito-borne pathogens: Red cedar in the southern Great Plains of the USA
(Springer Science and Business Media LLC, 2021-10-05)
West Nile virus (WNV) is the most significant mosquito-borne disease affecting humans in the United States. Eastern redcedar (ERC) is a native encroaching plant in the southern Great Plains that greatly alters abiotic ...
Flea-borne rickettsioses: Ecologic considerations
(Centers for Disease Control and Prevention (CDC), 1997-07)
Ecologic and economic factors, as well as changes in human behavior, have resulted in the emergence of new and the reemergence of existing but forgotten infectious diseases during the past 20 years. Flea-borne disease ...
Shiga toxin 2 overexpression in Escherichia coli O157:H7 strains associated with severe human disease
(Elsevier, 2011-12)
Variation in disease severity among Escherichia coli O157:H7 infections may result from differential expression of Shiga toxin 2 (Stx2). Eleven strains belonging to four prominent phylogenetic clades, including clade 8 ...