Browsing OSU - Faculty and Staff Publications by Subject "optical physics"
Now showing items 1-16 of 16
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Digital signal processor-based real-time optical Doppler tomography system
(SPIE, the international society for optics and photonics, 2004-05-01)We present a real-time data-processing and display unit, based on a custom-designed digital signal processor (DSP) module for imaging tissue structure and Doppler blood flow. The DSP module is incorporated into a conventional ... -
Effects of capsule on surface diffuse reflectance spectroscopy of the subcapsular parenchyma of a solid organ
(SPIE, the international society for optics and photonics, 2018-07-27)We hypothesize that the capsular optical properties and thickness combined affect how accurate the diffuse reflectance on the surface of a capsular solid organ represents that on the subcapsular parenchyma. Monte Carlo ... -
Flexible nine-channel photodetector probe facilitated intraspinal multisite transcutaneous photobiomodulation therapy dosimetry in cadaver dogs
(SPIE, the international society for optics and photonics, 2018-01-23)Noninvasive photobiomodulation therapy (PBMT) of spinal cord disease remains speculative due to the lack of evidence for whether photobiomodulatory irradiances can be transcutaneously delivered to the spinal cord under a ... -
Freehand diffuse optical spectroscopy imaging for intraoperative identification of major venous and arterial vessels underlying peritoneal fat: An in vivo demonstration in a pig model
(SPIE, the international society for optics and photonics, 2017-10-30)Inadvertent injury to important anatomic structures is a significant risk in minimally invasive surgery (MIS) that potentially requires conversion to an open procedure, which results in increased morbidity and mortality. ... -
Hybrid positron detection and optical coherence tomography system: Design, calibration, and experimental validation with rabbit atherosclerotic models
(SPIE, the international society for optics and photonics, 2005-07-01)We evaluate the performance of our novel hybrid optical coherence tomography (OCT) and scintillating probe, demonstrate simultaneous OCT imaging and scintillating detection, and validate the system using an atherosclerotic ... -
In vivo assessment of diet-induced rat hepatic steatosis development by percutaneous single-fiber spectroscopy detects scattering spectral changes due to fatty infiltration
(SPIE, the international society for optics and photonics, 2015-11-05)This study explores percutaneous single-fiber spectroscopy (SfS) of rat livers undergoing fatty infiltration. Eight test rats were fed a methionine-choline-deficient (MCD) diet, and four control rats were fed a normal diet. ... -
In vivo percutaneous reflectance spectroscopy of fatty liver development in rats suggests that the elevation of the scattering power is an early indicator of hepatic steatosis
(World Scientific Publishing, 2018-05-11)This study assessed whether there was a scattering spectral marker quantifiable by reflectance measurements that could indicate early development of hepatic steatosis in rats for potential applications to pre-procurement ... -
In vivo trans-rectal ultrasound-coupled near-infrared optical tomography of intact normal canine prostate
(World Scientific Publishing, 2009-07-01)This is the first tomography-presentation of the optical properties of a normal canine prostate, in vivo, in its native intact environment in the pelvic canal. The imaging was performed by trans-rectal near-infrared (NIR) ... -
In vivo trans-rectal ultrasound-coupled optical tomography of a transmissible venereal tumor model in the canine pelvic canal
(SPIE, the international society for optics and photonics, 2009-05-01)In vivo trans-rectal near-infrared (NIR) optical tomography was performed concurrently with, albeit reconstructed without spatial a prior of, trans-rectal ultrasound (US) on transmissible venereal tumor (TVT) developed as ... -
On the geometry dependence of differential pathlength factor for near-infrared spectroscopy. I. Steady-state with homogeneous medium
(SPIE, the international society for optics and photonics, 2015-10-14)This work analytically examines some dependences of the differential pathlength factor (DPF) for steady-state photon diffusion in a homogeneous medium on the shape, dimension, and absorption and reduced scattering coefficients ... -
Perspective review on solid-organ transplant: Needs in point-of-care optical biomarkers
(SPIE, the international society for optics and photonics, 2018-08-29)Solid-organ transplant is one of the most complex areas of modern medicine involving surgery. There are challenging opportunities in solid-organ transplant, specifically regarding the deficiencies in pathology workflow or ... -
Portable near-infrared diffusive light imager for breast cancer detection
(SPIE, the international society for optics and photonics, 2004-02-03)We present a frequency-domain near-infrared optical tomography system designed for breast cancer detection, in conjunction, with conventional ultrasound. It features fast optical switching, threewavelength excitations, and ... -
Toward transduodenal diffuse optical tomography of proximal pancreas
(Optica Publishing Group, 2013-10-10)We demonstrate the feasibility of diffuse optical tomography (DOT) of the proximal pancreas by using optical applicator channels deployed longitudinally along the exterior surface of a duodenoscope. As the duodenum that ... -
Towards non-contact glucose sensing in aqueous turbid medium at ∼1.1 meters distance
(Institute of Electrical and Electronics Engineers (IEEE), 2020-07-30)This work demonstrates a non-contact diffuse reflectance approach with a working distance of ∼1.1 meters for the potential of glucose sensing. Non-contact diffuse reflectance over 1.1-1.3 μm was developed according to a ... -
Trans-rectal ultrasound-coupled near-infrared optical tomography of the prostate. Part I: Simulation
(Optica Publishing Group, 2008-10-15)We investigate the feasibility of trans-rectal optical tomography of the prostate using an endo-rectal near-infrared (NIR) applicator that is to be integrated with a trans-rectal ultrasound (TRUS) probe. Integration with ... -
Trans-rectal ultrasound-coupled near-infrared optical tomography of the prostate. Part II: Experimental demonstration
(Optica Publishing Group, 2008-10-15)We demonstrate trans-rectal optical tomography of the prostate using an endo-rectal near-infrared (NIR) applicator integrated with a transrectal ultrasound (TRUS) probe. The endo-rectal NIR applicator incorporated a design ...