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Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1
(American Society for Microbiology, 2010-09)
The bacterial burden on human health is quickly outweighing available therapeutics. Our long-term goal is the development of antimicrobials with the potential for broad-spectrum activity. We previously reported phthalazine-based ...
Novel thermostable xylanase GH10 from Malbranchea pulchella expressed in Aspergillus nidulans with potential applications in biotechnology
(BioMed Central, 2014-07-29)
Background: The search for novel thermostable xylanases for industrial use has intensified in recent years, and thermophilic fungi are a promising source of useful enzymes. The present work reports the heterologous expression ...
Building a model: Developing genomic resources for common milkweed (Asclepias syriaca) with low coverage genome sequencing
(BioMed Central, 2011-05-04)
Background: Milkweeds (Asclepias L.) have been extensively investigated in diverse areas of evolutionary biology and ecology; however, there are few genetic resources available to facilitate and compliment these studies. ...
miR-27b inhibits fibroblast activation via targeting TGFB signaling pathway
(BioMed Central, 2017-01-17)
Background: MicroRNAs are a group of small RNAs that regulate gene expression at the posttranscriptional level. They regulate almost every aspect of cellular processes. In this study, we investigated whether miR-27b regulates ...
Greater neural adaptations following high- vs. low-load resistance training
(Frontiers Media, 2017-05-29)
We examined the neuromuscular adaptations following 3 and 6 weeks of 80 vs. 30% one repetition maximum (1RM) resistance training to failure in the leg extensors. Twenty-six men (age = 23.1 +/= 4.7 years) were randomly ...
Looking at the label and beyond: The effects of calorie labels, health consciousness, and demographics on caloric intake in restaurants
(BioMed Central, 2013-02-08)
Background: Recent legislation has required calorie labels on restaurant menus as a means of improving Americans' health. Despite the growing research in this area, no consensus has been reached on the effectiveness of ...
Evidence for WZ and ZZ production in final states with b-tagged jets
(2011-11-15)
We present evidence for the combined production of VZ (V = W or Z) events in final states containing charged leptons (electrons or muons) or neutrinos, and heavy flavor jets, using data collected by the D0 detector at the ...
Sex specific expression and distribution of small RNAs in papaya
(BioMed Central, 2014-01-13)
Background: Regulatory function of small non-coding RNAs (sRNA) in response to environmental and developmental cues has been established. Additionally, sRNA, also plays an important role in maintaining the heterochromatin ...
Broccoli (Brassica oleracea) phloem tissue proteome
(BioMed Central, 2013-11-07)
Background: The transport of sugars, hormones, amino acids, proteins, sugar alcohols, and other organic compounds from the sites of synthesis to the sites of use or storage occurs through the conducting cells of the phloem. ...
Application of the transtheoretical model to sedentary behaviors and its association with physical activity status
(Public Library of Science (PLoS), 2017-04-27)
Background: The Transtheoretical Model (TTM) is a successful framework for guiding behavior change programs for several health behaviors, yet its application to reduce of sedentary behavior has been neglected. In addition, ...