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Mapping of schistosomiasis and soil-transmitted helminths in Namibia: The first large-scale protocol to formally include rapid diagnostic tests
(Public Library of Science (PLoS), 2015-07-21)
Background: Namibia is now ready to begin mass drug administration of praziquantel and albendazole against schistosomiasis and soil-transmitted helminths, respectively. Although historical data identifies areas of transmission ...
Sigma factor n, liaison to an ntrC and rpoS dependent regulatory pathway controlling acid resistance and the LEE in enterohemorrhagic Escherichia coli
(Public Library of Science (PLoS), 2012)
Enterohemorrhagic Escherichia coli (EHEC) is dependent on acid resistance for gastric passage and low oral infectious dose, and the locus of enterocyte effacement (LEE) for intestinal colonization. Mutation of rpoN, encoding ...
Low seroprevalence of antibodies to Toxoplasma gondii in blood donors in central Namibia
(Informa UK Limited, 2014)
Although emphasis has been placed on research relating to human immunodeficiency virus (HIV), tuberculosis and malaria, several researchers in Africa are focusing on other threats to human health, such as neglected tropical ...
Risk assessment of flavivirus transmission in Namibia
(Elsevier BV, 2014-05-25)
The role of arboviruses causing acute febrile illness in sub-Saharan Africa is receiving more attention. Reports of dengue in tourists were published nearly 10 years ago in Namibia, but the current epidemiology of arboviruses ...
Risk of encountering questing ticks (Ixodidae) and the prevalence of tickborne pathogens in Oklahoma state parks
(Society of Southwestern Entomologists, 2018-06)
State parks, used by many for various kinds of recreation, are also places where people and their companion animals are exposed to ticks and tickborne pathogens. While most studies in state parks in the United States have ...
High prevalence of "Candidatus Rickettsia andeanae" and apparent exclusion of Rickettsia parkeri in adult Amblyomma maculatum (Acari: Ixodidae) from Kansas and Oklahoma
(Elsevier BV, 2015-03-13)
Amblyomma maculatum (the Gulf Coast tick), an aggressive, human-biting, Nearctic and Neotropical tick, is the principal vector of Rickettsia parkeri in the United States. This pathogenic spotted fever group Rickettsia ...
Updated distribution of Aedes albopictus in Oklahoma, and implications in arbovirus transmission
(The American Mosquito Control Association, 2015-03)
A series of statewide surveys were conducted in Oklahoma in the summers between 1991 and 2004 to identify the distribution of Aedes albopictus. Adult mosquitoes were identified in 63 counties, bringing the currently known ...
Exogenously scavenged and endogenously synthesized heme are differentially utilized by Mycobacterium tuberculosis
(American Society for Microbiology, 2022-10-26)
Heme is both an essential cofactor and an abundant source of nutritional iron for the human pathogen Mycobacterium tuberculosis. While heme is required for M. tuberculosis survival and virulence, it is also potentially ...
Reverse transcriptase PCR amplification of Rickettsia typhi from infected mammalian cells and insect vectors
(American Society for Microbiology, 1998-06)
We developed a reverse transcriptase PCR assay to detect expression of 120- and 17-kDa antigen genes in Rickettsia typhi. Infected Vero cell and flea RNAs were reverse transcribed by using random hexamers. The cDNA was ...
Mycobacteria, metals, and the macrophage
(Wiley, 2015-03)
Mycobacterium tuberculosis is a facultative intracellular pathogen that thrives inside host macrophages. A key trait of M. tuberculosis is to exploit and manipulate metal cation trafficking inside infected macrophages to ...