Now showing items 1-3 of 3

    • Mycobacteria, metals, and the macrophage 

      Neyrolles, Olivier; Wolschendorf, Frank; Mitra, Avishek; Niederweis, Michael (Wiley, 2015-03)
      Mycobacterium tuberculosis is a facultative intracellular pathogen that thrives inside host macrophages. A key trait of M. tuberculosis is to exploit and manipulate metal cation trafficking inside infected macrophages to ...
    • Role of the Mycobacterium tuberculosis ESX-4 secretion system in heme iron utilization and pore formation by PPE proteins 

      Sankey, November; Merrick, Haley; Singh, Padam; Rogers, Janet; Reddi, Amit; Hartson, Steven D.; Mitra, Avishek (American Society for Microbiology, 2023-02-07)
      Mycobacterium tuberculosis (Mtb) is transmitted through aerosols and primarily colonizes within the lung. The World Health Organization estimates that Mtb kills ~1.4 million people every year. A key aspect that makes Mtb ...
    • Shiga toxin 2 overexpression in Escherichia coli O157:H7 strains associated with severe human disease 

      Neupane, Mahesh; Abu-Ali, Galeb S.; Mitra, Avishek; Lacher, David W.; Manning, Shannon D.; Riordan, James T. (Elsevier, 2011-12)
      Variation in disease severity among Escherichia coli O157:H7 infections may result from differential expression of Shiga toxin 2 (Stx2). Eleven strains belonging to four prominent phylogenetic clades, including clade 8 ...