Browsing OSU - Patents Collection by Author "Berlin, Kenneth Darrell"
Now showing items 1-15 of 15
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3-7-diheterabicyclo (3.3.1)Nonanes and Derivatives as Antiarrhythmic Agents
Berlin, Kenneth Darrell; Thompson, Mark D.; Scherlag, Benjamin J.; Smith, Gary S.; Board of Regents/Oklahoma State University and the A & M Colleges (U.S. Patent and Trademark Office, 1993-12-07)3-7-Diheterabicyclo[3.3.1]nonanes and derivatives thereof are disclosed. Their method of preparation and use as antiarrhythmic agents is given. -
3-7-diheterabicyclo[3.3.1]Nonanes as Antiarrhythmic Agents
Berlin, Kenneth Darrell; Thompson, Mark D.; Scherlag, Benjamin J.; Smith, Gary S.; Board of Regents/Oklahoma State University and the A & M Colleges (U.S. Patent and Trademark Office, 1990-03-20)3-7,Diheterabicylo[3.3.1]nonanes and derivatives thereof are disclosed. Their method of preparation and use as antiarrhythmic agents is given. -
3-thia-7-azabicyclo(3.3.L)Nonanes and Derivatives as Antiarrhythmic Agents
Berlin, Kenneth Darrell; Scherlag, Benjamin J.; Bailey, Bruce R., III; Holt, Elizabeth M.; Oklahoma State University (U.S. Patent and Trademark Office, 1986-04-08)3-Thia-7-azabicyclo(3.3.1)nonanes and derivatives thereof are disclosed. The preparation of these compounds is given. Their use as antiarrhythmic agents is given. -
Azasteroids Compounds and Derivatives
Berlin, Kenneth Darrell; Durham, Norman Nevill; Desjardins, Claude; Board of Regents/Oklahoma State University and the A & M Colleges (U.S. Patent and Trademark Office, 1976-10-19)Azasteroids and certain derivatives each of a five ring system containing at least one aromatic nucleus and at least one nitrogen atom. The ring system is fused to a tetrahydrotetralin system or a tetrahydrophenanthrene ... -
Bis-1,3-diazine Heterocyclic Derivatives as Antiarrhythmic Agents
Berlin, Kenneth Darrell; Thompson, Mark D.; Scherlag, Benjamin J.; Smith, Gary S.; Oklahoma State University (U.S. Patent and Trademark Office, 1991-08-27)3-7-Diheterabicylo[3.3.1]nonanes and derivatives thereof are disclosed. Their method of preparation and use as antiarrhythmic agents is given. -
Certain 3-selena-7-aza-bicyclo[3.3.1]Nonanes as Antiarrhythmic Agents
Berlin, Kenneth Darrell; Thompson, Mark D.; Scherlag, Benjamin J.; Smith, Gary S.; Oklahoma State University (U.S. Patent and Trademark Office, 1988-10-18)3-7-Diheterabicylo[3.3.1]nonanes and derivatives thereof are disclosed. Their method of preparation and use as antiarrhythmic agents is given. -
Heteroarotinoid Compounds as Anticancer Agents
Berlin, Kenneth Darrell; Holt, Elizabeth M.; Ford, Warren T.; Thompson, Mark D.; Board of Regents/Oklahoma State University and the A & M Colleges (U.S. Patent and Trademark Office, 1989-05-02)Novel heteroarotinoid compositions characterized by the formulae: ##STR1## where R is H, CH.sub.3 or C.sub.2 H.sub.5 and X is S, S O, O, NCH.sub.3, Si(CH.sub.3).sub.2, N.sup.+ (H)CH.sub.3 [Cl.sup.- ], N.sup.+ (H)CH.sub.3 ... -
Heteroarotinoids as Anticancer Agents
Berlin, Kenneth Darrell; Ford, Warren T.; Rajadhyaksha, Shirish N.; Gale, Jonathan B.; Spruce, Lyle W.; Board of Regents/Oklahoma State University and the A & M Colleges (U.S. Patent and Trademark Office, 1989-05-23)Novel heteroarotinoid compositions characterized by the formulae: ##STR1## where: X is S or O; OAc is the acetate group ##STR2## and R is --H, --OH, --OCH.sub.3, or --OC.sub.2 H.sub.5 and includes ##STR3## for formulae (1) ... -
Heteroarotinoids as Anticancer Agents
Berlin, Kenneth Darrell; Ford, Warren T.; Rajadhyaksha, Shirish N.; Gale, Jonathan B.; Spruce, Lyle W.; Board of Regents/Oklahoma State University and the A & M Colleges (U.S. Patent and Trademark Office, 1990-12-11)Novel heteroarotinoid compositions characterized by the formulae: ##STR1## where: X is S or O; OAc is the acetate group ##STR2## and R is --H, --OH, --OCH.sub.3, or --OC.sub.2 H.sub.5 and includes ##STR3## for formulae (1) ... -
Heteroarotinoids Containing Urea or Thiourea Linker
Berlin, Kenneth Darrell; Benbrook, Doris M.; Nelson, Eldon C.; Board of Regents/Oklahoma State University and the A & M Colleges (U.S. Patent and Trademark Office, 2003-07-01)Compounds, known as heteroarotinoids, having varying abilities to inhibit growth of certain cancerous cells, induce normal cell differentiation, and induce apoptosis or death of cancerous cells, of the general formula: ... -
N-alkyl and N-acyl Derivatives of 3,7-diazabicyclo-[3.3.1]Nonanes and Selected Salts Thereof as Multi-class Antiarrhythmic Agents
Berlin, Kenneth Darrell; Garrison, Gregory L.; Sangiah, Subbiah; Clarke, Cyril R.; Chen, Chun-Lin; Lazzara, Ralph; Scherlag, Benjamin J.; Patterson, Eugene Stuart; Burrows, George E.; Board of Regents/Oklahoma State University and the A & M Colleges (U.S. Patent and Trademark Office, 1995-11-21)3,7-Diazabicyclo[3.3.1]nonanes and selected derivatives thereof of the general formula: ##STR1## are disclosed as multiclass antiarrhythmic agents. -
N-alkyl and N-acyl Derivatives of 3,7-diazabicyclo-[3.3.1]Nonanes and Selected Salts Thereof as Multi-class Antiarrhythmic Agents
Berlin, Kenneth Darrell; Garrison, Gregory L.; Sangiah, Subbiah; Clarke, Cyril R.; Chen, Chun-Lin; Lazzara, Ralph; Scherlag, Benjamin J.; Patterson, Eugene Stuart; Burrows, George Edward; Board of Regents/Oklahoma State University and the A & M Colleges (U.S. Patent and Trademark Office, 1998-07-28)3,7-Diazabicyclo[3.3]nonanes and selected derivatives thereof of the general formula: ##STR1## wherein Q=S; Z=CH.sub.2 ; and Y equals an N-acyl or N-alkyl group are disclosed as multiclass antiarrhythmic agents. -
Polyheterobicyclotridecane Compounds
Berlin, Kenneth Darrell; Thompson, Mark D.; Scherlag, Benjamin J.; Smith, Gary S.; Board of Regents/Oklahoma State University and the A & M Colleges (U.S. Patent and Trademark Office, 1990-12-25)3-7-Diheterabicyclo[3.3.1]nonanes and derivatives thereof are disclosed. Their method of preparation and use as antiarrhythmic agents is given. -
Salts of 3-azabicyclo [3.3.1]Nonanes as Antiarrhythmic Agents, and Precursors Thereof
Berlin, Kenneth Darrell; Scherlag, Benjamin J.; Clarke, Cyril R.; Otiv, Surendra R.; Zisman, Stan A.; Sangiah, Subbiah; Mulekar, Satish V.; Board of Regents/Oklahoma State University and the A & M Colleges (U.S. Patent and Trademark Office, 1992-01-28)Salts of 3-azabicyclo[3.3.1]nonanes are used in controlling antiarrhythmic processes and precursors thereof are disclosed. -
Salts of 3-azabicyclo[3.3.1]Nonanes as Antiarrhythmic Agents, and Precursors Thereof
Berlin, Kenneth Darrell; Scherlag, Benjamin J.; Clarke, Cyril R.; Otiv, Surendra R.; Zisman, Stan A.; Sangiah, Subbiah; Mulekar, Satish V.; Board of Regents/Oklahoma State University and the A & M Colleges (U.S. Patent and Trademark Office, 1992-05-05)Salts of 3-azabicyclo[3.3.1]nonanes are used in controlling antiarrhythmic processes and precursors thereof are disclosed.