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Applications of Hyphenated Analytical Techniques in Pharmaceutical Industry
(2011)
Analytical chemistry plays a critical role in pharmaceutical research and development. A typical analysis includes separating and identifying active pharmaceutical ingredients and impurities, determining the quantity of ...
STUDIES OF THE USE OF THE [2.2]PARACYCLOPHANE MOIETY TO MEDIATE INTERACTION BETWEEN METAL CENTERS AND ELECTROPOLYMERIZATION OF 2,2’-BITHIOPHENE IN MICELLAR MEDIA
(2013)
Organometallic polymers have been identified as a class of materials useful in various advanced applications due to their promising electrical, magnetic, optical and catalytic properties. Such properties depend on the ...
Study of Metal-Enhanced Fluorescence of Dye-Doped Silica Nanoparticles
(2012)
Enhancement of molecular fluorescence is of great interest due to the widespread popularity of fluorescence-based detection techniques available today. Although fluorescence-based detection is considered to be more sensitive ...
DEVELOPMENTS AND APPLICATIONS OF HIGH-THROUGHPUT TOP-DOWN PROTEOMICS
(2019)
Emerging technologies for liquid chromatography (LC) separations and mass spectrometry (MS) have dramatically improved the throughput of top-down proteomics, which has allowed the identification of thousands of intact ...
SELECTION OF METAL COMPLEX CATALYSTS BY TEMPLATING WITH TRANSITION STATE ANALOGS
(2015)
Abstract
Catalysts speed up reactions by providing an alternative, lower energy pathway for the reaction. However, the traditional method of catalyst discovery is time consuming and wastes chemicals. It is important to ...
MEASURING RATE CONSTANTS FOR THE REACTION OF HYPOCHLOROUS ACID AND BIOLOGICALLY RELEVANT MOLECULES
(2012)
Hypochlorous acid (HOCl) is a neutrophil-derived oxidant that is used to kill invading pathogens. Since HOCl reacts indiscriminately with biological molecules, such as amino acids, excess or misplaced production of HOCl ...
Effects of Insecticides on Postmortem Interval: Implications on Forensic Investigations
(2011)
Postmortem interval (PMI) is the length of time that occurs between death of a person and the subsequent discovery of the body. PMI can be determined in a variety of ways depending on how long the body has been exposed ...
Design and Synthesis of OSW-1 Analogs and Other Bioactive Small Molecules for Potential Therapeutic Applications
(2018)
OSW-1 is a cholestane glycoside natural product with potent anti-proliferative activity, broad spectrum anti-viral activity, and a novel mechanism of action. The OSW-1’s cellular targets are oxysterol-binding protein (OSBP) ...
Filamentous Biological Macromolecules Based Nanostructures and Their Applications
(2010)
In nanoscience, one promising strategy for achieving precise placements of nanomaterials and specific recognitions between individual build blocks is to use self-ordered templates to arrange them into designed pattern. ...
NATURAL PRODUCTS AS A SOURCE OF NEW THERAPIES FOR NEURODEGENERATIVE DISEASE AND EFFORTS TOWARD THE DEVELOPMENT OF A METABOLOMICS-BASED DRUG DISCOVERY PLATFORM
(2010)
Natural products have traditionally played an important role in drug discovery research. They have been particularly important in the search for therapies for neurodegenerative diseases. Although there are numerous forms ...