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Now showing items 11-20 of 22
Development of Contrast Agents for Optoacoustic Imaging
(2023-12-15)
Optoacoustic imaging is an emerging modality with inherent advantages relevant for clinical use. Following excitation of optoacoustic contrast agents with ultrashort (~10 ns) pulses of near-infrared light, thermoelastic ...
Translation and Development of Novel Annexin A5 - Protein Drug Conjugates for the Treatment of Triple-Negative Breast Cancer
(2022-12-16)
Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subset with limited targeted chemotherapies. TNBC is defined by the absence of the estrogen, progesterone, and HER2 hormonal receptors on the cell ...
Engineering a peptide-based tool for biomedical applications
(2022-12-16)
Numerous technological and scientific advancements have been developed by the structural organization and functional capabilities of natural materials. A field known as "biomaterials" focuses on adapting engineering concepts ...
Development of Patient-Specific Shape Memory Polymer Foams for the Treatment of Intracranial Aneurysms
(2023-05-12)
The objectives of this research include: (1) designing an electrically conductive shape memory polymer (SMP) material, (2) developing a method for the systematic fabrication of SMPs with complex three-dimensional geometries ...
Developing Novel Computer Aided Diagnosis Schemes for Improved Classification of Mammography Detected Masses
(2023-12-15)
Mammography imaging is a population-based breast cancer screening tool that has greatly aided in the decrease in breast cancer mortality over time. Although mammography is the most frequently employed breast imaging modality, ...
Neuroimaging biomarkers for noninvasive brain stimulation in Mal de Débarquement syndrome
(2021-08-05)
This dissertation summarizes my work to identify biomarkers for neuromodulation treatment in Mal de Débarquement Syndrome (MdDS) using resting state EEG and fMRI. Biomarkers that are associated with the symptom changes ...
Peptide Aggregation Induced Immunogenic Cell Death
(2022-12-16)
Cell death is an inevitable biological outcome, every living thing dies. However, how cells die is an important question and ultimately is decisive in homeostasis and disease progression. Immune system is in the center of ...
Mapping brain activity and resting-state functional connectivity with functional near-infrared spectroscopy
(2022-08-04)
Functional near-infrared spectroscopy (fNIRS) as a non-invasive optical imaging technique to measure cerebral hemodynamics has seen rapid development and increasing use in studying the human brain. fNIRS measures relative ...
Forward-view Endoscopic Optical Coherence Tomography for Needle-based Interventions
(2024-05-10)
Needle-based interventions (NBIs) are procedures that require a minimally invasive approach
to gain access to tissue structures of interest. Each year, more than 30 million of these
interventions are performed in the US. ...
Synthetic chondroinductive biomaterial for hyaline cartilage regeneration
(2024-05-10)
Avascularity, low cell count, and low proliferative potential constitute the triad that defines the limited self-regenerative potential of articular cartilage. Consequently, the repair of articular cartilage defects presents ...