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Molecular and biochemical basis of dark-cutting beef
(2022-12)
Dark-cutting beef is a meat quality defect where beef fails to have a characteristic bright-red color typical of normal-pH beef. The occurrence of dark-cutting beef is associated with a high muscle pH resulting from defective ...
Characterizing mechanisms of potential inhibitors of the Hsp90 chaperone complex
(2023-05)
In this work, we characterized the effects of ten compounds reported to be inhibitors of the Hsp90 chaperone complex in Jurkat leukemia cells, and compared them to the N-terminal Hsp90 inhibitor AUY922. Our primary focus ...
Maintenance energy requirements, postpartum reproduction, and ruminal temperature at parturition and estrus of beef cows
(2009-05)
Scope and Method of Study: Angus x Hereford cows were used to determine the effects of postpartum weight gain (WG) and treatment with bovine somatotropin (bST) on concentrations of hormones in plasma and calf growth. Cows ...
Molecular characterization of aromatic hydrocarbon degradation in extreme halophiles
(2014-07)
Many hypersaline environments such as natural saline lakes, salt marshes, saline industrial effluents, oil fields and coastal areas are often contaminated with high levels of petroleum hydrocarbons. Since non-halophiles ...
Quantitative Transcriptome and Proteome Analyses of Immunity-related Molecules in Manduca Sexta Larval Hemolymph
(Oklahoma State University, 2012-07-01)
This study explores immunity-related molecules in Manduca sexta larvae by studying the quantitative change of mRNAs and proteins after immune challenge. To investigate the mRNA level changes, we isolated mRNA samples from ...
Leveraging -omics based approaches to explore environments: A look at two domains of life
(2022-05)
Rapid advancements in technology have both dramatically lowered the cost of sequencing as well as increased the depth of information gleaned. With such a low barrier of entry, increasing numbers of scientists around the ...
Characterizing the proteomic and mitochondrial functional differences between normal-pH and dark-cutting beef
(2019-12)
Dark-cutting beef is an example of color deviation, in which beef fails to have a characteristic bright-red color. The overall goal of the current research was to determine the biochemical basis of dark-cutting beef. Two ...
Proteomics fingerprints of AUY922 and 17-DMAG indicate common mechanisms of action for Hsp90 inhibitors
(2013-12)
In this work, we identified the proteomics fingerprint of the anti-cancer drug candidate AUY922 in Jurkat leukemia cells and compared AUY922's fingerprint to the proteomics fingerprints of flagship Hsp90 inhibitors 17-DMAG ...
Effect of water stress on the expression of proteins in hard red spring wheat Triticum aestivum cv. Butte 86
(2008-12)
Scope and Method of Study: Environmental changes including water stress affect the wheat quality and yield. This study attempts to explore the effect of water stress on the storage and specific organelle proteins' expression ...