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Molecular and biochemical basis of dark-cutting beef
(2022-12)
Dark-cutting beef is a meat quality defect where beef fails to have a characteristic bright-red color typical of normal-pH beef. The occurrence of dark-cutting beef is associated with a high muscle pH resulting from defective ...
Characterizing mechanisms of potential inhibitors of the Hsp90 chaperone complex
(2023-05)
In this work, we characterized the effects of ten compounds reported to be inhibitors of the Hsp90 chaperone complex in Jurkat leukemia cells, and compared them to the N-terminal Hsp90 inhibitor AUY922. Our primary focus ...
Leveraging -omics based approaches to explore environments: A look at two domains of life
(2022-05)
Rapid advancements in technology have both dramatically lowered the cost of sequencing as well as increased the depth of information gleaned. With such a low barrier of entry, increasing numbers of scientists around the ...