Browsing OSU - Electronic Theses and Dissertations by Author "Wagner, Jarrad R."
Now showing items 1-17 of 17
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Analysis and Distribution of Thc, 11-oh-thc and Thc-cooh in Postmortem Fluids and Tissues
Saenz, Sunday Renee (2016-07-01)Marijuana is the most commonly abused illicit drug worldwide. The psychoactive compound ?9-tetrahydrocannabinol (THC) can be found in Cannabis sativa and provides a euphoric feeling, distorted sense of time, and loss of ... -
Analysis of Synthetic Cannabinoids in Urine via Solid Phase Extraction and Liquid Chromatography with Tandem Mass Spectrometry (LC-MS/MS)
Dickerson, Kristin LeAnn (2016-07-01)Synthetic cannabinoids have emerged as a dangerous new trend in illicit drug use.The appointment of many popular synthetic cannabinoids as Schedule I controlledsubstances has helped to decrease their popularity in recent ... -
Characterization of Cannabinoids in Cannabidiol (CBD) Products
Lopez, McCayla (2019-05-01)The purpose of this research was to determine what cannabinoids other than cannabidiol (CBD) can be found in various CBD products, as well as determine their legality. CBD is federally a Schedule I drug, although CBD ... -
Comparison of Chiral Methamphetamine Separations in Urine
Carlson, Kylene Casey (2018-05-01)Methamphetamine (meth) and amphetamine are commonly abused central nervous system (CNS) stimulants that are frequently screened for in many forensic and clinical toxicology labs. Amphetamine is present as the metabolite ... -
Comparison of High-Resolution Mass Spectrometry with Immunoassay in Qualitative Urine Drug Screening
Fisk, Paige (2019-05-01)Liquid Chromatography Time-of-Flight Mass Spectrometry (LC-TOF) utilizes a high-resolution mass spectrometer and chromatography to identify drugs in urine, based on their exact masses and retention times. The current "gold ... -
Comparison of Hydrolysis Efficiencies of Multiple Beta-Glucuronidase Enzymes
Revelle, Jessica (2018-05-01)In urine drug testing for pain management, dilute and shoot is a common specimen preparation method. Urine contains the parent form of drugs, as well as metabolites. Beta-glucuronidases are enzymes that are used to cleave ... -
Development of an Analytical Method for VInca Alkaloids Using Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Ngo, Minh Trieu (Oklahoma State University, 2010-08-01)The purpose of this study was to develop and validate an analytical method for vinblastine (VBL) and deacetylvinblastine (DVBL) using liquid chromatography tandem mass spectrometry (LC/MS/MS). The goal of the study was to ... -
Environmental contamination from clandestine drug manufacture
Ciesielski, Austin Lee (2020-05)Drug abuse and drug seizures are on the rise across the United States. As drug prevalence increases, the public is more likely to come into contact with drugs, drug-contaminated locations, or sites of drug production. These ... -
Environmental impacts of One Pot methamphetamine clandestine laboratories - Characterization and detection of trace materials
Green, Matthew Kevin (2017-05)The One Pot methamphetamine production method has become the primary method of choice in clandestine drug laboratories across the United States, due to its simplicity and the availability of required materials. While the ... -
Evaluation of Oral Fluid as a Specimen to Detect Controlled Substances
Veitenheimer, Allison (Oklahoma State University, 2016-05-01)Drugged driving has become more prevalent than drunk driving and is quickly gaining national attention due to increased prescription drug abuse and recent cannabis legalization. Unlike alcohol, police officers do not ... -
Evaluation of Sweat as an Evidential Specimen in Drug-facilitated Sexual Assault
Robertson, Dana Charles (2016-05-01)Drug-facilitated sexual assault (DFSA) investigations can be hindered by delayed reporting or victim unwillingness to fully participate in a physical examination. In turn, biological evidence collected to prove incapacitation ... -
Method Development for the Detection of Synthetic Cathinones and Investigation of Their Metabolism Using Human Microsomes
Brachtenbach, Travis John (2016-07-01)Abuse of designer drugs such as synthetic cathinones presents a challenge to both medical and forensic experts. Detecting cathinone exposure in humans requires a sensitive, reliable method and treatment involves an ... -
Pharmacokinetic scaling of anticancer drugs in dogs
Achanta, Satyanarayana (2012-07)Scope and Method of Study: Anticancer drugs are characterized by a narrow therapeutic index and wide inter-individual variability in therapeutic outcome, disposition, and toxicity. The accurate calculation and administration ... -
RNA-seq of biological fluids for the evaluation of mRNA degradation in relation to sample age
Weinbrecht, Katelyn Deane (2014-07)Research on the forensic applications of RNA analysis has increased greatly in the last decade. Defined uses of RNA in forensic analysis include the use of RNA to identify tissue type, determine sample age, and play a role ... -
Role of glutamate in corneal nociception
Ibitokun, Bernadette Olayinka (2012-07)Scope and Method of Study: At sensory peripheral nerve terminals, glutamate is released into tissues, e.g., skin, where it sensitizes surrounding afferent nerves and resident cells. Sensitization of peripheral sensory ... -
Urine Drug Testing Via Volumetric Absorptive Microsampling Tips
Welch, Katlyn (2018-05-01)Presently, laboratories typically perform urine drug testing with collected urine specimens using the dilute and shoot extraction technique. While the dilute and shoot technique is a functional means of evaluation for ...