Browsing by Author "Picking, William D."
Now showing items 1-8 of 8
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Analysis of Coxiella burnetii mediated modulation of host cells during infection
Mahapatra, Saugata (2011-07)Scope and Method of Study: Scope - To determine Coxiella burnetii mediated modulation of host cell during infection. Methods for microbiological and molecular analyses include: eukaryotic and prokaryotic cell culture, ... -
Broadly Protective Shigella Vaccine Based on Type III Secretion Apparatus Proteins
Picking, Wendy L.; Picking, William D.; Board of Regents/Oklahoma State University and the A & M Colleges (U.S. Patent and Trademark Office, 2016-11-15)Broad-based, cross-protective, O-serotype independent vaccines against Shigella and related pathogenic organisms are provided. The vaccines comprise one or more of the type III secretion (TTS) apparatus needle proteins ... -
Forster resonance energy transfer (FRET) as a tool for dissecting the molecular mechanisms for maturation of the Shigella type III secretion needle tip complex
Dickenson, Nicholas E.; Picking, William D. (MDPI, 2012-11-16)Forster resonance energy transfer (FRET) provides a powerful tool for monitoring intermolecular interactions and a sensitive technique for studying A-level protein conformational changes. One system that has particularly ... -
Investigation of the protein-protein and protein-lipid interactions of IpaB from Shigella flexneri
Adam, Philip Robert (2014-05)Shigella spp. are a major cause of morbidity and mortality in the developing world, causing over 125 million cases of diarrhea annually. Like many Gram-negative pathogens, Shigella utilizes a type three secretion system ... -
Structure-function relationships in the photoactive yellow protein family of photoreceptors
Rathod, Rachana Ramila Suresh (2014-12)The amino acid sequence of a protein determines its three-dimensional structure, which in turn determines its functional properties. An intensively studied but still partially unresolved question is how the structure of a ... -
Use of the salmonella SPP type III secretion proteins as a protective vaccination
Picking, Wendy L.; Picking, William D.; The Board of Regents for Oklahoma State University; University of Kansas (U.S. Patent and Trademark Office, 2022-10-11)Antigenic molecules and compositions described herein protect against infection by typhoidal and non-typhoidal Salmonella serovars. Methods of immunization comprise the use of the antigenic molecules. -
Use of the Salmonella spp type III secretion proteins as a protective vaccination
Picking, Wendy L.; Picking, William D.; Board of Regents/Oklahoma State University and the A & M Colleges; University of Kansas (U.S. Patent and Trademark Office, 2020-02-04)Antigenic molecules and compositions described herein protect against infection by typhoidal and non-typhoidal Salmonella serovars. Methods of immunization comprise the use of the antigenic molecules. -
Use of the Salmonella Spp Type III Secretion Proteins as a Protective Vaccination
Picking, Wendy L.; Picking, William D.; Board of Regents/Oklahoma State University and the A & M Colleges; University of Kansas (U.S. Patent and Trademark Office, 2018-04-24)Antigenic molecules and compositions described herein protect against infection by typhoidal and non-typhoidal Salmonella serovars. Methods of immunization comprise the use of the antigenic molecules.