The research described by this dissertation has focused on the fabrication and design, for the improvement of lead chalcogenide lasers. The ultimate goal was to develop TE-cooled single-mode continuous wave Mid-IR laser for high resolution spectroscopic applications. Processing techniques and procedures as well as theoretical design have been successfully developed that could lead to high temperature single-mode continuous wave (CW) laser operation. Light emitting Pb-salt structures on BaF2 substrate has been examined. An antireflection coating material, for diode-pumped Pb-salt light emitters, that has enhanced room temperature continuous wave light emission has been described. A new surface preparation technology for epi-ready [110] oriented BaF2 substrates and a novel mounting technique for the fabrication of cleaved cavity Pb-salt laser grown on {110} BaF2 was developed. Lasing results from [110] oriented Pb-salt laser fabricated on PbSnSe substrate have been reported for the first time. Theoretical modeling of a Pb-Salt ridge waveguide laser for single lateral mode operation and the development of a fabrication process for the same has been described. A novel fabrication method of cleaved facet Pb-salt laser on as-grown metal substrate for high temperature operation of the device has been described.