Sequencing of Multiple Clostridial Genomes Related to Biomass Conversion and Biofuel Production

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dc.contributor.authorHemme, Christopher L.
dc.contributor.authorMouttaki, Housna
dc.contributor.authorLee, Yong-Jin
dc.contributor.authorHe, Zhili
dc.contributor.authorWu, Liyou
dc.contributor.authorVan Nostrand, Joy D.
dc.contributor.authorLawson, Paul A.
dc.contributor.authorTanner, Ralph S.
dc.contributor.authorStevenson, Bradley S.
dc.contributor.authorMcInerney, Michael J.
dc.contributor.authorHuhnke, Raymond L.
dc.contributor.authorZhou, Jizhong
dc.contributor.authoret al.
dc.date.accessioned2015-05-27T22:10:47Z
dc.date.accessioned2016-03-30T15:34:25Z
dc.date.available2015-05-27T22:10:47Z
dc.date.available2016-03-30T15:34:25Z
dc.date.issued2010-12
dc.description.abstractModern methods to develop microbe-based biomass conversion processes require a system-level understanding of the microbes involved. Clostridium species have long been recognized as ideal candidates for processes involving biomass conversion and production of various biofuels and other industrial products. To expand the knowledge base for clostridial species relevant to current biofuel production efforts, we have sequenced the genomes of 20 species spanning multiple genera. The majority of species sequenced fall within the class III cellulosome-encoding Clostridium and the class V saccharolytic Thermoanaerobacteraceae. Species were chosen based on representation in the experimental literature as model organisms, ability to degrade cellulosic biomass either by free enzymes or by cellulosomes, ability to rapidly ferment hexose and pentose sugars to ethanol, and ability to ferment synthesis gas to ethanol. The sequenced strains significantly increase the number of noncommensal/nonpathogenic clostridial species and provide a key foundation for future studies of biomass conversion, cellulosome composition, and clostridial systems biology.en_US
dc.description.peerreviewYesen_US
dc.identifier.doi10.1128/JB.01064-10en_US
dc.identifier.urihttp://hdl.handle.net/11244/14644
dc.languageen_USen_US
dc.relation.ispartofseriesJournal of Bacteriology;192:24
dc.relation.urihttp://jb.asm.org/content/192/24/6494
dc.subjectBiology, Microbiology.en_US
dc.titleSequencing of Multiple Clostridial Genomes Related to Biomass Conversion and Biofuel Productionen_US
dc.typeArticleen_US
ou.groupCollege of Arts and Sciences::Department of Microbiology and Plant Biologyen_US

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