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Genome-Wide DNA Methylation Maps in Follicular Lymphoma Cells Determined by Methylation-Enriched Bisulfite Sequencing
(PLos One, 2010-09-29)
BackgroundFollicular lymphoma (FL) is a form of non-Hodgkin's lymphoma (NHL) that arises from germinal center (GC) B-cells. Despite the significant advances in immunotherapy, FL is still not curable. Beyond transcriptional ...
Physiological Roles of ArcA, Crp, and EtrA and Their Interactive Control on Aerobic and Anaerobic Respiration in Shewanella oneidensis
(PLos One, 2010-12-28)
In the genome of Shewanella oneidensis, genes encoding the global regulators ArcA, Crp, and EtrA have been identified. All these proteins deviate from their counterparts in E. coli significantly in terms of functionality ...
Ecosystem Carbon Stock Influenced by Plantation Practice: Implications for Planting Forests as a Measure of Climate Change Mitigation
(PLos One, 2010-05-27)
Uncertainties remain in the potential of forest plantations to sequestrate carbon (C). We synthesized 86 experimental studies with paired-site design, using a meta-analysis approach, to quantify the differences in ecosystem ...
Functional Biogeography as Evidence of Gene Transfer in Hypersaline Microbial Communities
(PLos One, 2010-09-23)
BackgroundHorizontal gene transfer (HGT) plays a major role in speciation and evolution of bacteria and archaea by controlling gene distribution within an environment. However, information that links HGT to a natural ...
Ultrasound-Mediated DNA Transformation in Thermophilic Gram-Positive Anaerobes
(PLos One, 2010-09-04)
BackgroundThermophilic, Gram-positive, anaerobic bacteria (TGPAs) are generally recalcitrant to chemical and electrotransformation due to their special cell-wall structure and the low intrinsic permeability of plasma ...
Fruit and Soil Quality of Organic and Conventional Strawberry Agroecosystems
(PLos One, 2010-09-01)
BackgroundSale of organic foods is one of the fastest growing market segments within the global food industry. People often buy organic food because they believe organic farms produce more nutritious and better tasting ...
Psychedelics and the Human Receptorome
(PLos One, 2010-02-02)
We currently understand the mental effects of psychedelics to be caused by agonism or partial agonism of 5-HT2A (and possibly 5-HT2C) receptors, and we understand that psychedelic drugs, especially phenylalkylamines, are ...
First Investigation of the Microbiology of the Deepest Layer of Ocean Crust
(PLos One, 2010-11-05)
The gabbroic layer comprises the majority of ocean crust. Opportunities to sample this expansive crustal environment are rare because of the technological demands of deep ocean drilling; thus, gabbroic microbial communities ...