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Now showing items 41-47 of 47
Insights from Characterizing Extinct Human Gut Microbiomes
(PLos One, 2012-12-12)
In an effort to better understand the ancestral state of the human distal gut microbiome, we examine feces retrieved from archaeological contexts (coprolites). To accomplish this, we pyrosequenced the 16S rDNA V3 region ...
Shared and Unique Patterns of Embryo Development in Extremophile Poeciliids
(PLos One, 2011-11-07)
Background Closely related lineages of livebearing fishes have independently adapted to two extreme environmental factors: toxic hydrogen sulphide (H2S) and perpetual darkness. Previous work has demonstrated in ...
First Investigation of the Microbiology of the Deepest Layer of Ocean Crust
(PLos One, 2010-11-05)
The gabbroic layer comprises the majority of ocean crust. Opportunities to sample this expansive crustal environment are rare because of the technological demands of deep ocean drilling; thus, gabbroic microbial communities ...
Temperature Sensitivity of Soil Organic Carbon Mineralization along an Elevation Gradient in the Wuyi Mountains, China
(PLos One, 2013-01-14)
Soil organic carbon (SOC) actively participates in the global carbon (C) cycle. Despite much research, however, our understanding of the temperature sensitivity of soil organic carbon (SOC) mineralization is still very ...
Mannose-Binding Lectin 2 Gene and Risk of Adult Glioma
(PLos One, 2013-04-18)
Background and AimsThe immune system is likely to play a key role in the etiology of gliomas. Genetic polymorphisms in the mannose-binding lectin gene, a key activator in the lectin complement pathway, have been associated ...
Immunodominance of Antigenic Site B over Site A of Hemagglutinin of Recent H3N2 Influenza Viruses
(PLos One, 2012-07-25)
H3N2 influenza viruses have now circulated in the human population for 43 years since the pandemic of 1968, accumulating sequence changes in the hemagglutinin (HA) and neuraminidase (NA) that are believed to be predominantly ...
Structure and Dynamics of Amyloid-β Segmental Polymorphisms
(PLos One, 2012-07-24)
It is believed that amyloid-beta (Aβ) aggregates play a role in the pathogenesis of Alzheimer’s disease. Aβ molecules form β-sheet structures with multiple interaction sites. This polymorphism gives rise to differences in ...