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Association of IFIH1 and pro-inflammatory mediators: Potential new clues in SLE-associated pathogenesis
(PLos One, 2017-02-24)
Antiviral defenses are inappropriately activated in systemic lupus erythematosus (SLE) and association between SLE and the antiviral helicase gene, IFIH1, is well established. We sought to extend the previously reported ...
Elimination of Chromosomal Island SpyCIM1 from Streptococcus pyogenes Strain SF370 Reverses the Mutator Phenotype and Alters Global Transcription
(PLos One, 2015-12-23)
Streptococcus pyogenes chromosomal island M1 (SpyCIM1) integrates by site-specific recombination into the 5’ end of DNA mismatch repair (MMR) gene mutL in strain SF370SmR, blocking transcription of it and the downstream ...
Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis
(PLos One, 2015-08-18)
Doublecortin-like kinase 1 (Dclk1), a microtubule-associated kinase, marks the fifth lineage of intestinal epithelial cells called tuft cells that function as tumor stem cells in Apc mutant models of colon cancer. In order ...
A late-surviving apatemyid (Mammalia: Apatotheria) from the latest Oligocene of Florida, USA
(2015-12-17)
A new species of Apatemyidae, Sinclairella simplicidens, is based on four isolated teeth that were screenwashed from fissure fillings at the late Oligocene Buda locality, Alachua County, Florida. Compared to its only ...
Hexavalent Chromium Reduction under Fermentative Conditions with Lactate Stimulated Native Microbial Communities
(PLos One, 2013-12-23)
Microbial reduction of toxic hexavalent chromium (Cr(VI)) in-situ is a plausible bioremediation strategy in electron-acceptor limited environments. However, higher Cr(VI) may impose stress on syntrophic communities and ...
Undergraduate Conductors’ and Conducting Teachers’ Perceptions of Basic Conducting Efficacy
(Update: Applications of Research in Music Education, 2014-10-23)
The purpose of this study was to examine undergraduate conductors’ and conducting teachers’ perceptions about basic conducting efficacy. At the beginning and end of the semester, undergraduate students (N = 19) enrolled ...
Proteomics Coupled with Metabolite and Cell Wall Profiling Reveal Metabolic Processes of a Developing Rice Stem Internode
(2017-07-13)
Internodes of grass stems function in mechanical support, transport, and, in some species, are a major sink organ for carbon in the form of cell wall polymers. This study reports cell wall composition, proteomic, and ...
Curcumin Prevents Palmitoylation of Integrin β4 in Breast Cancer Cells
(PLos One, 2015-05-04)
Curcumin has been shown to mitigate cancer phenotypes such as invasive migration, proliferation, and survival by disrupting numerous signaling pathways. Our previous studies showed that curcumin inhibits integrin β4 (ITG ...
Central or Peripheral: Reconsidering the Place of African Americans within the American Intellectual Establishment
(2015-12)
Do we think of Frederick Douglass as a founding father of the modern social democratic tradition in the United States? Or is he taken as proof in our textbooks that a slave could indeed become a “great American”—proof that, ...
Psyche in New York: The Devil Wears Prada Updates the Myth
(2012)
The Psyche myth tells the story of a goddess guiding a younger woman’s path to maturity, blocking her way by imposing impossible tasks that teach her about being an adult. The movie The Devil Wears Prada retells the myth ...