dc.contributor.advisor | Gilliland, Stanley E. | |
dc.contributor.author | Guillen, Lacey Michele | |
dc.date.accessioned | 2013-11-26T08:22:34Z | |
dc.date.available | 2013-11-26T08:22:34Z | |
dc.date.issued | 2009-05 | |
dc.identifier.uri | https://hdl.handle.net/11244/6598 | |
dc.description.abstract | Scope and Method of Study: The purpose of this experiment was to investigate the possible mechanisms responsible for the success of the direct-fed microbials, Lactobacillus acidophilus and Propionibacterium freudenreichii (included in and marketed as Bovamine(R), in controlling Escherichia coli O157:H7 in cattle. In order to do this an E. coli O157:H7 challenge was conducted with ten steers. Five were fed the direct-fed microbials and five were fed the control treatment, lactose (direct-fed microbial carrier). Immunoglobulins, blood chemistry, complete blood counts, performance measures, and carriage of E. coli O157:H7 were measured throughout the trial. | |
dc.description.abstract | Findings and Conclusions: An increased level of serum IgA was observed in the direct-fed microbial group post-challenge. The direct-fed microbial group also showed an increased amount of blood granulocytes and granulocytes as a percentage of white blood cells post-challenge. The direct-fed microbial group had a higher post challenge increase in total lymphocytes while the control group had higher lymphocytes as a percentage of white blood cells post-challenge. The control group had higher dry matter intakes. Both groups exhibited similar levels of all measurements prior to the challenge. | |
dc.format | application/pdf | |
dc.language | en_US | |
dc.rights | Copyright is held by the author who has granted the Oklahoma State University Library the non-exclusive right to share this material in its institutional repository. Contact Digital Library Services at lib-dls@okstate.edu or 405-744-9161 for the permission policy on the use, reproduction or distribution of this material. | |
dc.title | Determination of the mechanism(s) by which direct-fed microbials control Escherichia coli O157:H7 in cattle | |
dc.contributor.committeeMember | Krehbiel, Clinton R. | |
dc.contributor.committeeMember | McGlynn, William G. | |
dc.contributor.committeeMember | Stoecker, Barbara J. | |
osu.filename | Guillen_okstate_0664D_10201.pdf | |
osu.accesstype | Open Access | |
dc.type.genre | Dissertation | |
dc.type.material | Text | |
dc.subject.keywords | blood chemistry | |
dc.subject.keywords | cattle | |
dc.subject.keywords | direct-fed microbials | |
dc.subject.keywords | e. coli o157:h7 | |
dc.subject.keywords | immune | |
thesis.degree.discipline | Animal Science | |
thesis.degree.grantor | Oklahoma State University | |