Browsing OSU - Honors College Theses by Author "Canaan, Patricia"
Now showing items 1-16 of 16
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Classification of Elizabethkingia anophelis resistance mechanisms and characterization of novel B-lactamase genes
Purcell, Lindsey (2018-05-11)Due to the cause of recent outbreaks within regions of the United States and other parts of the world, the study of Elizabethkingia anophelis has been of great interest due to high mortality and presence of multiple ... -
Deciphering the role of the INI-1 protein within the SWI/SNF remodeling complex
Henry, Kayla (5/4/2023)INI-1 is a core subunit of the SWI/SNF chromatin remodeling complex, which stands for SWItch/Sucrose Non-Fermentable, and is a known tumor suppressor gene. INI-1 is a 47kDa long protein with 385 amino acids present in its ... -
Differential expression of Elizabethkingia anophelis to cefotaxime and imipenem
Pearson, James (2017-05-12)Elizabethkingia anophelis is a beta-lactam antibiotic resistant bacterium that uses a variety of mechanisms to express this resistance. It is currently unknown how E. anophelis responds when exposed to different beta-lactam ... -
Effects of green algal concentrations on the life history characteristics of Daphnia magna
Gore, Jessica (2020-05-08)As eutrophication levels continue to rise, it is important to understand how increases in algal biomass will affect other food web components. In this study, we used Scenedesmus acutus, a species of green algae, to determine ... -
Fluoroquinolone resistance in Elizabethkingia bruuniana
Irwin, Russell (2020-04-29)The Gram-negative bacterial genus Elizabethkingia displays natural multiple antimicrobial resistance and is an emerging pathogen. One of the therapeutic agents still effective in the treatment of the Elizabethkingia are ... -
Lack of access to care hurts rural populations' health: Federally qualified health centers offer a solution
Dockrey, Danielle (2017-05-10)The objective of this thesis is to investigate the effectiveness of implementing more Federally Qualified Health Centers (FQHCs) into rural areas to improve existing health disparities. Three benefits of FQHCs were analyzed: ... -
Localization and structure of plastidial-encoded polymerase sub-units
Guerrero Criado, Andres Eduardo (2016-04-26)Chloroplast biogenesis is a quintessential process In plants for the acquisition of photo-autotrophy. The path towards chloroplast biogenesis begins with the inhibition of skotomorphogenesis (That is the growth program in ... -
Mechanism of lysosomal cathepsin B degradation of Cryptococcus neoformans
Cannon, Brinley (2020-04-29)Cryptococcus neoformans is an opportunistic fungal pathogen that is spread through inhalation and predominantly causes disease in immunocompromised patients. The infection begins in the lungs as pneumonia and can disseminate ... -
N-Glycosyltransferase (ApNGT) and the in-vitro glycosylation of y-Sarcoglycan
Blair, Eston W. (2018-05-01)N-Glycosyltransferase of Actinobacillus pleuropneumoniae (ApNGT) is an enzyme which performs N-linked glycosylation of proteins. Furthermore, ApNGT is a cytoplasmic glycosyltransferase with the ability to target heterologous ... -
Phosphorylation effects on cancer protein's DNA binding
Luttrell, Carlee (2017-12-15)This study is focused on understanding the phosphorylation sites within INI-1 DNA binding domains to understand the INI-1 protein's connections to atypical teraroid/rhadboid tumor (AT/RT), an aggressive pediatric neural ... -
Phylogenetic variety and importance in the b-lactamases of Elizabethkingia; anophilis, miracola and meningoseptica in pathogenicity
Guerrero Criado, Andres Eduardo (2016-04-29)With recent outbreaks of Elizabethkingia affecting the United States, it is important to further understand the method of action that this bacterium uses to infect patients. Given that Elizabethkingia is not regarded as a ... -
Potential in vitro competitive inhibition of Bacillus spp. strains with possible bioactive additives against a Salmonella pathogen strain via well diffusion
Wiseman, Thomas (2017-05-03)There were two objectives set for this research project. The first objective of this experiment was to determine potential competitive inhibition between different strains of Bacillus spp. and pathogenic bacteria. The ... -
Proteomic analysis of ethanol reduced susceptibility mutants
Marquart, Hadassah (2020-05-13)Staphylococcus aureus are dangerous pathogens responsible for thousands of deaths every year, and it is estimated that 95 million Americans may be carriers of a S. aureus strain (1). Even more dangerous is the subset of ... -
Quantitative analysis of exo-enzymatic activity in Bacillus subtilis using commercial assay procedures
Murie, Maeghan (2016-04-28)Probiotics are health-benefiting organisms that are useful supplements in the maintenance of homeostasis within a host's body. The Bacillus genus is currently considered the best alternative for use as probiotics because ... -
Structural investigation of the male European Corn Borer's pheromone binding protein-3
Bishop, Benton Miller (2018-05-11)European Corn Borer (Ostrinia nubilalis) is an economically impacting moth of the North American agricultural community. First introduced to the United States in 1917, Ostrinia nubilalis now causes a yearly sum of approximately ... -
Using lipid nanodiscs for the in vitro glycosylation of membrane proteins
Dolan, Rachel (2022-04-29)Membrane proteins are involved in a number of human diseases are important to study. Due to the fact that these proteins are, by nature, insoluble in aqueous solutions, they require detergent or lipid environments that ...