Show simple item record

dc.contributor.authorLivingston, Reagan
dc.contributor.authorDaher, Nadim
dc.date.accessioned2023-11-02T20:46:38Z
dc.date.available2023-11-02T20:46:38Z
dc.date.issued2023-02-17
dc.identifierouhd_Livingston_unusualpresentationofrecurrent_2023
dc.identifier.citationLivingston, R., and Daher, N. (2023, February 17). Unusual presentation of a recurrent asthmatic with bronchiectasis on multiple computed topographies. Poster presented at Research Week, Oklahoma State University Center for Health Sciences, Tulsa, Ok.
dc.identifier.urihttps://hdl.handle.net/11244/339909
dc.description.abstractRecurrent treatment resistant asthma in high risk patient populations may be the inciting factor that leads to further evaluation of other contributing etiologies of a patient’s symptoms. Allergic bronchopulmonary Aspergillus (ABPA) is primarily an immunologic response that is most commonly seen in asthmatics and cystic fibrosis patients. Common presentation will include symptoms of hemoptysis, fever, weight-loss, malaise as well as transient and fleeting pulmonary opacities and bronchiectasis on imaging. ABPA is classified as an allergic respiratory mycosis against Aspergillus fumigatus, and has a higher incidence seen in asthmatic specialty clinics as well as those in the intensive care unit.
dc.description.abstractThe pathogenesis of ABPA is not fully understood, but is thought to be due to difficulty with clearance of the airways in genetically predisposed patients as well as T-helper 2 cell immune response. In these genetically predisposed patients, they are unable to clear the Aspergillus fumigatus conida from their airways which subsequently germinates into hyphae leading to a activation of the adaptive immune response and release of both chemokines and cytokines. This ultimately leads to development of a large inflammatory response with mast cell degranulation, recruitment of eosinophils and neutrophils, and the development of the characteristic immunologic response seen in ABPA as well as progression to bronchiectasis and pulmonary fibrosis.
dc.formatapplication/pdf
dc.languageen_US
dc.publisherOklahoma State University Center for Health Sciences
dc.rightsThe author(s) retain the copyright or have the right to deposit the item giving the Oklahoma State University Library a limited, non-exclusive right to share this material in its institutional repository. Contact Digital Resources and Discovery Services at lib-dls@okstate.edu or 405-744-9161 for the permission policy on the use, reproduction or distribution of this material.
dc.titleUnusual presentation of a recurrent asthmatic with bronchiectasis on multiple computed topographies
osu.filenameouhd_Livingston_unusualpresentationofrecurrent_2023.pdf
dc.type.genrePresentation
dc.type.materialText
dc.subject.keywordsallergic
dc.subject.keywordsbronchopulmonary
dc.subject.keywordsaspergillosis
dc.subject.keywordsasthmatic
dc.subject.keywordsbrochiectasis


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record