Research Week 2022
Recent Submissions
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Morphine potentiates glucocorticoid receptor translocation in neuronal cells
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: The hypothalamic-pituitary-adrenal (HPA) axis plays a central role in regulating signaling by glucocorticoid receptor which is expressed in almost all cells. Adrenocorticotropin hormone (ACTH) and β-endorphin ... -
Accuracy of the lever sign test in a diagnostic exam of an acute anterior cruciate ligament (ACL) injury: a critically appraised topic
(Oklahoma State University Center for Health Sciences, 2022-02-18)Context: The lever sign has been developed and researched, within the last ten years, as an alternative physical examination of the anterior cruciate ligament (ACL). The simplicity and practicality of the test has increased ... -
Archaea in mammalian gut microbiomes
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: Archaea are the most enigmatic domain of the three domains of life. Archaea are unique in that they share some characteristics with bacteria and others with eukaryotes while they are also distinct from these ... -
Sex differences in protein excretion in mice consuming high protein diet
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: Normally, the renal excretion of protein (or proteinuria) is absent or very small. Ingesting high-protein diets can elevate proteinuria and in the long term, increase the work on the kidney by increasing ... -
Study of time dependent degradation of mRNA encoding the SPRR3 and S100A9 gene markers in saliva stains
(Oklahoma State University Center for Health Sciences, 2022-02-18)When a body fluid stain is found at a crime scene, it may be beneficial to use the RNA found within to approximate the age of the stain. This is important in cases where a person of interest has been known to be in a ... -
Asthma call back survey results: a need for increase of asthma actions plans and allowance to carry medication
(Oklahoma State University Center for Health Sciences, 2022-02-18)Purpose of Research: Asthma is the most common chronic disease affecting children in the United States. Goals for asthma management include symptom control, ability to maintain a normal activity level, and minimizing adverse ... -
Breastfeeding status and its influence on Native American women’s food preferences
(Oklahoma State University Center for Health Sciences, 2022-02-18)Introduction: To evaluate if breastfeeding alters Native American women’s food preferences, recently postpartum women were offered food interest surveys during their 6-week postpartum checkup at W. W. Hastings Indian ... -
Clinical trial discontinuation and non-publication for the pharmacologic treatment of Post-Traumatic Stress Disorder among military veterans
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: Failures by researchers and clinicians to understand, confront, and overcome barriers in veteran-health research may result in the waste of finite resources. Research waste includes clinical trial discontinuation ... -
Trauma across generations: a novel look at adverse childhood experiences using the Behavioral Risk Factor Surveillance System
(Oklahoma State University Center for Health Sciences, 2022-02-18)Introduction: The adverse childhood experiences (ACEs) study was one of the first to demonstrate the robust, life-long effects of family dysfunction, child maltreatment, and neglect during childhood. The initial study of ... -
COVID 19 and its effects on pediatric orthopaedic clinical trials
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: Clinical trials for the treatment of pediatric orthopaedics are critical to enhance the quality of life of these children. In response to the COVID-19 pandemic, the FDA updated guidance on conducting clinical ... -
Adverse childhood experiences and subjective cognitive decline: An analysis of the Behavioral Risk Factor Surveillance System
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: Cognitive functioning plays a crucial role in maintaining a healthy, active, and independent lifestyle. A 2017 study found the total net cost of care for an individual with dementia was 175% more than a person ... -
Proteomics study reveals a gender-based ribosomal inflammatory biomarker in Hepatitis C virus induced cirrhosis
(Oklahoma State University Center for Health Sciences, 2022-02-18)Hepatitis C Virus (HCV) infection is a major cause of Hepatocellular Carcinoma (HCC). Further, HCC is a leading cause of liver-related death world-wide linked to liver cirrhosis and chronic liver disease. Clinical evidence ... -
Cultural pathway to osteopathic medical school: The Native American pre-admissions workshop
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: Native Americans (NAs) experience significant health disparities compared to the general US population. Medical education has a key role to play in addressing these inequities; however, it is currently falling ... -
Effectiveness of whole-body vibration on improving balance in athletes with chronic ankle instability
(Oklahoma State University Center for Health Sciences, 2022-02-18)Context: Chronic ankle instability is a condition that can occur after multiple ankle injuries, or one severe ankle injury, and can affect balance, proprioception and walking mechanics. Improving balance can be helpful in ... -
Examining trends in the public’s awareness of exocrine pancreatic insufficiency in the United States using infodemiology metrics
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: Exocrine Pancreatic Insufficiency (EPI) is a disorder caused by multiple etiologies leading to decreased pancreatic function. EPI presents with nonspecific symptoms and is largely unknown by the public, making ... -
Synthetic cannabinoid, WIN 55212-2, leads to changes of proBDNF/BDNF ratio levels in the periaqueductal gray and blood concentrations in the adolescent rat
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: The hemp plant Cannabis sativa—marijuana and hashish are among the most commonly used illicit substances in adolescents and young adults. The synthetic CB1 agonist WIN 55212-2 (WIN) administration to rats and ... -
Person-centered language and ADHD research: a cross-sectional examination of stigmatizing language within medical literature
(Oklahoma State University Center for Health Sciences, 2022-02-18)Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that is frequently found in children. It often goes untreated due to the negative stigma that surrounds the disorder. This stigma is often ... -
Investigation of the microbial and molecular correlates of Morgellons disease
(Oklahoma State University Center for Health Sciences, 2022-02-18)Morgellons disease is a complex dermopathy that is controversial in the medical community. Unfortunately, there is not enough evidence to the etiology or transmission of this disease. Due to the lack of information, the ... -
Gender and geographical representation in the National Institute of Health’s Neuroscience and Behavior Study Section (AA4): a longitudinal analysis
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: Previous studies support the experience of gender and geographical bias in research scientists that receive funding from the National Institute of Health (NIH) in terms of the application success rate and the ... -
Analysis of changing statistical significance from .05 to .005 in foot and ankle randomized controlled trials
(Oklahoma State University Center for Health Sciences, 2022-02-18)Background: Misinterpretation of p-values in RCTs is extremely problematic since they are the core basis for high levels of recommendation in clinical practice guidelines, especially Orthopaedics. Benjamin et al. proposed ...