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Hybrid positron detection and optical coherence tomography system: Design, calibration, and experimental validation with rabbit atherosclerotic models

dc.contributor.authorPiao, Daqing
dc.contributor.authorSadeghi, Mehran M.
dc.contributor.authorZhang, Jiasheng
dc.contributor.authorChen, Yueli
dc.contributor.authorSinusas, AJ
dc.contributor.authorZhu, Quing
dc.date.accessioned2023-07-07T16:36:30Z
dc.date.available2023-07-07T16:36:30Z
dc.date.issued2005-07-01
dc.identifieroksd_piao_hybrid_positron_detection_and_2005
dc.identifier.citationPiao, D., Sadeghi, M.M., Zhang, J., Chen, Y., Sinusas, A.J., Zhu, Q. (2005). Hybrid positron detection and optical coherence tomography system: Design, calibration, and experimental validation with rabbit atherosclerotic models. Journal of Biomedical Optics, 10(4), 044010-1-044010-10. https://doi.org/10.1117/1.1954773
dc.identifier.issn1083-3668
dc.identifier.urihttps://hdl.handle.net/11244/337916
dc.description.abstractWe evaluate the performance of our novel hybrid optical coherence tomography (OCT) and scintillating probe, demonstrate simultaneous OCT imaging and scintillating detection, and validate the system using an atherosclerotic rabbit model. Preliminary data obtained from the rabbit model suggest that our prototype positron probe detects local uptake of fluorodeoxyglucose (FDG) labeled with F positron (beta) radionuclide emitter, and the high-uptake regions correlate with sites of injury and extensive atherosclerosis areas. Preliminary data also suggest that coregistered high-resolution OCT images provide imaging of detailed plaque microstructures, which cannot be resolved by positron detection.
dc.formatapplication/pdf
dc.languageen_US
dc.publisherSPIE, the international society for optics and photonics
dc.relation.ispartofJournal of Biomedical Optics, 10 (4)
dc.relation.urihttps://www.ncbi.nlm.nih.gov/pubmed/16178644
dc.rightsThis material has been previously published. In the Oklahoma State University Library's institutional repository this version is made available through the open access principles and the terms of agreement/consent between the author(s) and the publisher. The permission policy on the use, reproduction or distribution of the material falls under fair use for educational, scholarship, and research purposes. Contact Digital Resources and Discovery Services at lib-dls@okstate.edu or 405-744-9161 for further information.
dc.titleHybrid positron detection and optical coherence tomography system: Design, calibration, and experimental validation with rabbit atherosclerotic models
dc.date.updated2023-07-03T14:42:29Z
dc.noteopen access status: Bronze OA
dc.identifier.doi10.1117/1.1954773
dc.description.departmentElectrical and Computer Engineering
dc.type.genreArticle
dc.type.materialText
dc.subject.keywordsfluid mechanics and thermal engineering
dc.subject.keywordsbiomedical and clinical sciences
dc.subject.keywordsengineering
dc.subject.keywordsbiomedical imaging
dc.subject.keywordsaging
dc.subject.keywordsbioengineering
dc.subject.keywordscardiovascular
dc.subject.keywordsatherosclerosis
dc.subject.keywordsevaluation of markers and technologies
dc.subject.keywordsdetection, screening and diagnosis
dc.subject.keywordsoptical physics
dc.subject.keywordsoptics
dc.subject.keywordsophthalmology and optometry
dc.subject.keywordsatomic, molecular and optical physics
dc.subject.keywordsanimals
dc.subject.keywordscalibration
dc.subject.keywordscatheters, indwelling
dc.subject.keywordsdisease models, animal
dc.subject.keywordsequipment design
dc.subject.keywordsequipment failure analysis
dc.subject.keywordsfluorodeoxyglucose f18
dc.subject.keywordsimage enhancement
dc.subject.keywordspositron-emission tomography
dc.subject.keywordsrabbits
dc.subject.keywordsradionuclide imaging
dc.subject.keywordsradiopharmaceuticals
dc.subject.keywordssubtraction technique
dc.subject.keywordssystems integration
dc.subject.keywordstomography, optical coherence
dc.subject.keywordstransducers
dc.identifier.authorORCID: 0000-0003-0922-6885 (Piao, D)
dc.identifier.authorScopusID: 7005153312 | 57220465193 (Piao, D)
dc.identifier.authorResearcherID: I-1341-2013 (Piao, D)
dc.identifier.authorScopusID: 35599478400 (Sadeghi, MM)
dc.identifier.authorScopusID: 55720125300 (Zhang, J)
dc.identifier.authorScopusID: 8380855900 (Chen, Y)
dc.identifier.authorScopusID: 7006837185 (Sinusas, AJ)
dc.identifier.authorScopusID: 7403313690 (Zhu, Q)
dc.identifier.essn1560-2281


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