dc.contributor.author | Piao, Daqing | |
dc.contributor.author | Sypniewski, Lara A. | |
dc.contributor.author | Bailey, Christian | |
dc.contributor.author | Dugat, Danielle | |
dc.contributor.author | Burba, Daniel J. | |
dc.contributor.author | De Taboada, Luis | |
dc.date.accessioned | 2023-07-06T19:28:17Z | |
dc.date.available | 2023-07-06T19:28:17Z | |
dc.date.issued | 2018-01-23 | |
dc.identifier | oksd_piao_flexible_nine_channel_photodetector_2018 | |
dc.identifier.citation | Piao, D., Sypniewski, L.A., Bailey, C., Dugat, D., Burba, D.J., De Taboada, L. (2018). Flexible nine-channel photodetector probe facilitated intraspinal multisite transcutaneous photobiomodulation therapy dosimetry in cadaver dogs. Journal of Biomedical Optics, 23(1), 010503-010503. https://doi.org/10.1117/1.JBO.23.1.010503 | |
dc.identifier.issn | 1083-3668 | |
dc.identifier.uri | https://hdl.handle.net/11244/337899 | |
dc.description.abstract | Noninvasive photobiomodulation therapy (PBMT) of spinal cord disease remains speculative due to the lack of evidence for whether photobiomodulatory irradiances can be transcutaneously delivered to the spinal cord under a clinically acceptable PBMT surface irradiation protocol. We developed a flexible nine-channel photodetection probe for deployment within the spinal canal of a cadaver dog after hemilaminectomy to measure transcutaneously transmitted PBMT irradiance at nine sites over an eight-cm spinal canal length. The probe was built upon a 6.325-mm tubular stem, to the surface of which nine photodiodes were epoxied at approximately 1 cm apart. The photodiode has a form factor of 4.80 mm×2.10 mm×1.15 mm (length×width×height). Each photodiode was individually calibrated to deliver 1 V per 7.58 μW/cm2 continuous irradiance at 850 nm. The outputs of eight photodiodes were logged concurrently using a data acquisition module interfacing eight channels of differential analog signals, while the output of the ninth photodiode was measured by a precision multimeter. This flexible probe rendered simultaneous intraspinal (nine-site) measurements of transcutaneous PBMT irradiations at 980 nm in a pilot cadaver dog model. At a surface continuous irradiance of 3.14 W/cm2 applied off-contact between L1 and L2, intraspinal irradiances picked up by nine photodiodes had a maximum of 327.48 μW/cm2 without the skin and 5.68 μW/cm2 with the skin. | |
dc.format | application/pdf | |
dc.language | en_US | |
dc.publisher | SPIE, the international society for optics and photonics | |
dc.relation.ispartof | Journal of Biomedical Optics, 23 (1) | |
dc.relation.uri | https://www.ncbi.nlm.nih.gov/pubmed/29363291 | |
dc.rights | This material has been previously published. In the Oklahoma State University Library's institutional repository this version is made available through the open access principles and the terms of agreement/consent between the author(s) and the publisher. The permission policy on the use, reproduction or distribution of the material falls under fair use for educational, scholarship, and research purposes. Contact Digital Resources and Discovery Services at lib-dls@okstate.edu or 405-744-9161 for further information. | |
dc.title | Flexible nine-channel photodetector probe facilitated intraspinal multisite transcutaneous photobiomodulation therapy dosimetry in cadaver dogs | |
dc.date.updated | 2023-07-02T13:30:50Z | |
dc.note | open access status: Gold OA | |
osu.filename | oksd_piao_flexible_nine_channel_photodetector_2018.pdf | |
dc.identifier.doi | 10.1117/1.JBO.23.1.010503 | |
dc.description.department | Electrical & Computer Engineering | |
dc.description.department | Veterinary Clinical Sciences | |
dc.type.genre | Article | |
dc.type.material | Text | |
dc.subject.keywords | biomedical and clinical sciences | |
dc.subject.keywords | clinical sciences | |
dc.subject.keywords | physical sciences | |
dc.subject.keywords | rare diseases | |
dc.subject.keywords | dosimetry | |
dc.subject.keywords | low-level light therapy | |
dc.subject.keywords | photobiomodulation therapy | |
dc.subject.keywords | spinal cord injury | |
dc.subject.keywords | optical physics | |
dc.subject.keywords | optics | |
dc.subject.keywords | ophthalmology and optometry | |
dc.subject.keywords | biomedical engineering | |
dc.subject.keywords | atomic, molecular and optical physics | |
dc.subject.keywords | animals | |
dc.subject.keywords | cadaver | |
dc.subject.keywords | calibration | |
dc.subject.keywords | diffusion | |
dc.subject.keywords | dogs | |
dc.subject.keywords | light | |
dc.subject.keywords | low-level light therapy | |
dc.subject.keywords | muscle, skeletal | |
dc.subject.keywords | needles | |
dc.subject.keywords | radiometry | |
dc.subject.keywords | skin | |
dc.subject.keywords | spinal cord diseases | |
dc.subject.keywords | surface properties | |
dc.identifier.author | ORCID: 0000-0003-0922-6885 (Piao, D) | |
dc.identifier.author | ScopusID: 7005153312 | 57220465193 (Piao, D) | |
dc.identifier.author | ResearcherID: I-1341-2013 (Piao, D) | |
dc.identifier.author | ORCID: 0000-0001-7420-1188 (Sypniewski, LA) | |
dc.identifier.author | ScopusID: 57189005116 (Sypniewski, LA) | |
dc.identifier.author | ScopusID: 57200412492 (Bailey, C) | |
dc.identifier.author | ORCID: 0000-0003-4760-6096 (Dugat, D) | |
dc.identifier.author | ScopusID: 50861136600 | 36114737300 | 57208885301 (Dugat, D) | |
dc.identifier.author | ScopusID: 6603673536 (Burba, DJ) | |
dc.identifier.author | ScopusID: 8937840900 (De Taboada, L) | |
dc.identifier.essn | 1560-2281 | |