dc.contributor.author | Piao, Daqing | |
dc.contributor.author | Borron, Halen | |
dc.contributor.author | Hawxby, Alan | |
dc.contributor.author | Wright, Harlan | |
dc.contributor.author | Rubin, Erin M. | |
dc.date.accessioned | 2023-07-06T19:28:08Z | |
dc.date.available | 2023-07-06T19:28:08Z | |
dc.date.issued | 2018-07-27 | |
dc.identifier | oksd_piao_effects_of_capsule_on_2018 | |
dc.identifier.citation | Piao, D., Borron, H., Hawxby, A., Wright, H., Rubin, E.M. (2018). Effects of capsule on surface diffuse reflectance spectroscopy of the subcapsular parenchyma of a solid organ. Journal of Biomedical Optics, 23(12), 121602-121602. https://doi.org/10.1117/1.JBO.23.12.121602 | |
dc.identifier.issn | 1083-3668 | |
dc.identifier.uri | https://hdl.handle.net/11244/337898 | |
dc.description.abstract | We hypothesize that the capsular optical properties and thickness combined affect how accurate the diffuse reflectance on the surface of a capsular solid organ represents that on the subcapsular parenchyma. Monte Carlo simulations on two-layer geometries evaluated how a thin superficial layer with the thickness from 10 to 1000μm affected the surface diffuse reflectance over a source-detector separation spanning 0.01 to 10 mm. The simulations represented the superficial layer presenting various contrasts concerning refractive index, anisotropy factor, absorption coefficient, and reduced scattering coefficient, versus those of the subsurface main medium. An analytical approach modeled the effects of the superficial layer of various thicknesses and optical properties on diffuse reflectance. Diffuse reflectance spectroscopy was performed ex vivo on 10 fresh human livers and 9 fresh human kidneys using a surface probe with a 3-mm source-detector separation. The difference of the device-specific diffuse reflectance on the organ between with the capsule and without the capsule has significantly greater spectral variation in the kidney than in the liver. The significantly greater spectral deviation of surface diffuse reflectance between with and without the capsule in the kidney than in the liver was analytically accountable by considering the much thicker capsule of the kidney than of the liver. | |
dc.format | application/pdf | |
dc.language | en_US | |
dc.publisher | SPIE, the international society for optics and photonics | |
dc.relation.ispartof | Journal of Biomedical Optics, 23 (12) | |
dc.relation.uri | https://www.ncbi.nlm.nih.gov/pubmed/30054997 | |
dc.rights | This material has been previously published. In the Oklahoma State University Library's institutional repository this version is made available through the open access principles and the terms of agreement/consent between the author(s) and the publisher. The permission policy on the use, reproduction or distribution of the material falls under fair use for educational, scholarship, and research purposes. Contact Digital Resources and Discovery Services at lib-dls@okstate.edu or 405-744-9161 for further information. | |
dc.title | Effects of capsule on surface diffuse reflectance spectroscopy of the subcapsular parenchyma of a solid organ | |
dc.date.updated | 2023-07-02T13:29:39Z | |
dc.note | open access status: Gold OA | |
osu.filename | oksd_piao_effects_of_capsule_on_2018.pdf | |
dc.identifier.doi | 10.1117/1.JBO.23.12.121602 | |
dc.description.department | Electrical & Computer Engineering | |
dc.type.genre | Article | |
dc.type.material | Text | |
dc.subject.keywords | biomedical and clinical sciences | |
dc.subject.keywords | clinical sciences | |
dc.subject.keywords | physical sciences | |
dc.subject.keywords | liver disease | |
dc.subject.keywords | kidney disease | |
dc.subject.keywords | digestive diseases | |
dc.subject.keywords | capsule | |
dc.subject.keywords | diffuse optical spectroscopy | |
dc.subject.keywords | diffuse reflectance spectroscopy | |
dc.subject.keywords | functional near-infrared spectroscopy | |
dc.subject.keywords | light-tissue interaction | |
dc.subject.keywords | optical physics | |
dc.subject.keywords | optics | |
dc.subject.keywords | ophthalmology and optometry | |
dc.subject.keywords | biomedical engineering | |
dc.subject.keywords | atomic, molecular and optical physics | |
dc.subject.keywords | anisotropy | |
dc.subject.keywords | computer simulation | |
dc.subject.keywords | diffusion | |
dc.subject.keywords | humans | |
dc.subject.keywords | kidney | |
dc.subject.keywords | light | |
dc.subject.keywords | liver | |
dc.subject.keywords | models, theoretical | |
dc.subject.keywords | monte carlo method | |
dc.subject.keywords | refractometry | |
dc.subject.keywords | scattering, radiation | |
dc.subject.keywords | spectrophotometry | |
dc.subject.keywords | spectrum analysis | |
dc.identifier.author | ORCID: 0000-0003-0922-6885 (Piao, D) | |
dc.identifier.author | ScopusID: 7005153312 | 57220465193 (Piao, D) | |
dc.identifier.author | ResearcherID: I-1341-2013 (Piao, D) | |
dc.identifier.author | ScopusID: 57202230404 (Borron, H) | |
dc.identifier.author | ScopusID: 6507412061 (Hawxby, A) | |
dc.identifier.author | ScopusID: 7202463116 (Wright, H) | |
dc.identifier.author | ScopusID: 57202237829 (Rubin, EM) | |
dc.identifier.essn | 1560-2281 | |