dc.contributor.author | Crittell, Rachel | |
dc.date.accessioned | 2023-06-01T21:40:27Z | |
dc.date.available | 2023-06-01T21:40:27Z | |
dc.date.issued | 4/18/2023 | |
dc.identifier.uri | https://hdl.handle.net/11244/337782 | |
dc.description.abstract | For many years, investigations on nitrogenous heterocycles have been an essential part of organic chemistry due to their widespread use in medications. Our research examines alternative ways to prepare nitrogen-containing heteroarenes while minimizing the formation of unwanted by-products. Many of our target molecules have structural similarities with biologically active compounds that are commonly used for numerous conditions, such as cancer, anxiety, and fungal infections. By optimizing a preliminary procedure from the Bolliger lab, we were able to improve the isolated yields for the iodine-promoted cyclization step. In this presentation, we will discuss the results of our cyclization reaction and discuss possible reaction mechanisms. Ultimately, we hope our research will pave a pathway to novel species with biologically relevant functional groups. | |
dc.format | application/pdf | |
dc.language | en_US | |
dc.rights | Copyright is held by the author who has granted the Oklahoma State University Library the non-exclusive right to share this material in its institutional repository. Contact Digital Library Services at lib-dls@okstate.edu or 405-744-9161 for the permission policy on the use, reproduction or distribution of this material. | |
dc.title | Access to tricyclic heteroarenes by an iodine-promoted cyclization reaction | |
osu.filename | oksd_crittell_access_to_tricyclic_heteroarenes_2023.pdf | |
osu.accesstype | Open Access | |
dc.type.genre | Honors Thesis | |
dc.type.material | Text | |
dc.contributor.director | Bolliger, Jeanne | |
dc.contributor.facultyreader | Fennell, Christopher | |
thesis.degree.discipline | Chemistry | |
thesis.degree.grantor | Oklahoma State University | |