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dc.contributor.authorRailey, Ashley F.
dc.contributor.authorMuller, Clemma
dc.contributor.authorNoonan, Carolyn
dc.contributor.authorSchmitter-Edgecombe, Maureen
dc.contributor.authorSinclair, Ka’imi
dc.contributor.authorKim, Corin
dc.contributor.authorLook, Mele
dc.contributor.authorKaholokula, J Keawe'aimoku
dc.date.accessioned2022-11-07T14:34:51Z
dc.date.available2022-11-07T14:34:51Z
dc.date.issued2022-01
dc.identifier.citationRailey, A.F., Muller, C., Noonan, C., Schmitter-Edgecombe, M., Sinclair, K., Kim, C., Look, M., Kaholokula, J.K.A. (2022). Cost Effectiveness of a Cultural Physical Activity Intervention to Reduce Blood Pressure Among Native Hawaiians with Hypertension. PharmacoEconomics - Open, 6(1), pp. 85-94. https://doi.org/10.1007/s41669-021-00291-6
dc.identifier.issn2509-4262
dc.identifier.urihttps://hdl.handle.net/11244/336607
dc.description.abstractObjective: The aim of this study was to calculate the costs and assess whether a culturally grounded physical activity intervention offered through community-based organizations is cost effective in reducing blood pressure among Native Hawaiian adults with hypertension. Methods: Six community-based organizations in Hawai'i completed a randomized controlled trial between 2015 and 2019. Overall, 263 Native Hawaiian adults with uncontrolled hypertension (≥ 140 mmHg systolic, ≥ 90 mmHg diastolic) were randomized to either a 12-month intervention group of hula (traditional Hawaiian dance) lessons and self-regulation classes, or to an education-only waitlist control group. The primary outcome was change in systolic blood pressure collected at baseline and 3, 6, and 12 months for the intervention compared with the control group. Incremental cost-effectiveness ratios (ICERs) were calculated for primary and secondary outcomes. Non-parametric bootstrapping and sensitivity analyses evaluated uncertainty in parameters and outcomes. Results: The mean intervention cost was US$361/person, and the 6-month ICER was US$103/mmHg reduction in systolic blood pressure and US$95/mmHg in diastolic blood pressure. At 12 months, the intervention group maintained reductions in blood pressure, which exceeded reductions for usual care based on blood pressure outcomes. The change in blood pressure at 12 months resulted in ICERs of US$100/mmHg reduction in systolic blood pressure and US$93/mmHg in diastolic blood pressure. Sensitivity analyses suggested that at the estimated intervention cost, the probability that the program would lower systolic blood pressure by 5 mmHg was 67 and 2.5% at 6 and 12 months, respectively. Conclusion: The 6-month Ola Hou program may be cost effective for low-resource community-based organizations. Maintenance of blood pressure reductions at 6 and 12 months in the intervention group contributed to potential cost effectiveness. Future studies should further evaluate the cost effectiveness of indigenous physical activity programs in similar settings and by modeling lifetime costs and quality-adjusted life-years. Trial registration number: NCT02620709.
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dc.languageen_US
dc.publisherSpringer Nature
dc.relation.ispartofPharmacoEconomics - Open, 6 (1)
dc.relation.urihttp://dx.doi.org/10.1007/s41669-021-00291-6
dc.rightsThis material has been previously published. In the Oklahoma State University Library's institutional repository this version is made available through the open access principles and the terms of agreement/consent between the author(s) and the publisher. The permission policy on the use, reproduction or distribution of the material falls under fair use for educational, scholarship, and research purposes. Contact Digital Resources and Discovery Services at lib-dls@okstate.edu or 405-744-9161 for further information.
dc.titleCost effectiveness of a cultural physical activity intervention to reduce blood pressure among Native Hawaiians with hypertension
dc.date.updated2022-11-03T21:15:14Z
dc.noteopen access status: Gold OA
dc.identifier.doi10.1007/s41669-021-00291-6
dc.description.departmentSociology
dc.type.genreArticle
dc.type.materialText
dc.subject.keywordsCost Effectiveness Research
dc.subject.keywordsComparative Effectiveness Research
dc.subject.keywordsHypertension
dc.subject.keywordsClinical Trials and Supportive Activities
dc.subject.keywordsPrevention
dc.subject.keywordsClinical Research
dc.subject.keywordsCardiovascular
dc.subject.keywordsPrimary prevention interventions to modify behaviors or promote well-being
dc.subject.keywordsPrevention of disease and conditions, and promotion of well-being
dc.identifier.authorORCID: 0000-0002-0763-5397 (Railey, Ashley F)
dc.identifier.essn2509-4254


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