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Now showing items 211-220 of 277
Estimating a rural-urban PCP workload disparity: caring for smokers
(Oklahoma State University Center for Health Sciences, 2022-02-18)
Background: Smokers are concentrated in rural America. CDC reports 28.5% of rural Americans smoke versus 25.1% of urban Americans. The workload impact of those additional smokers in a rural primary care practice has not ...
Osteopathic academic heritage of OSU-COM
(Oklahoma State University Center for Health Services, 2020-02-28)
BACKGROUND: In 1892, Dr. Andrew Taylor Still founded the field of Osteopathic Medicine by publishing The Philosophy and Mechanical Principles of Osteopathy when his philosophy of holistic medicine and tenets of osteopathic ...
Influence of COVID-19 on contraception: a cross-sectional analysis of disrupted clinical trials
(Oklahoma State University Center for Health Sciences, 2022-02-18)
Background: The COVID-19 pandemic exacerbated barriers to contraceptive services and disrupted the progression of ongoing clinical trials (CTs) in several fields of medicine1–4, including contraceptive care. Further, ...
Decreased serum levels of proBDNF, but not mature BDNF during adolescent oxycodone intoxication preceding long-term social neglect and harsh environmental conditions
(Oklahoma State University Center for Health Sciences, 2022-02-18)
Background: Adolescent opioid addiction is a global problem with a significant social and economic burden in the United States. Several studies have suggested that BDNF (mature BDNF) and its precursor play an essential ...
Proteomics study reveals a hydroxysteroid dehydrogenase (HSD) as a sex-based biomarker in Hepatitis C virus induced cirrhosis
(Oklahoma State University Center for Health Sciences, 2022-02-18)
Hepatitis C virus (HCV) infection-related inflammation, liver fibrosis and cirrhosis often lead to development of hepatocellular carcinoma (HCC). In the United States, 4.6 million people are infected with HCV. Studies show ...
Identification of critical virulence factors of fusobacterium nucleatum in promoting colorectal carcinoma
(Oklahoma State University Center for Health Sciences, 2023-02-17)
Background: The presence of an oral commensal, Fusobacterium nucleatum, in colorectal cancer(CRC) has been identified as an indicator of poor prognosis and has also been shown to increase gradually from stage I to IV. ...
Pediatric autoimmune clinical trial discontinuation and non-publication: An analysis of the National Library of Medicine
(Oklahoma State University Center for Health Sciences, 2023-02-17)
Background: With the rise in pediatric autoimmune diseases in the United States, it is both clinically relevant and timely to analyze the safety, cost-effectiveness, and efficacy of treatment options. The methodical research ...
Evaluation of systematic review utilization in the development of OB-GYN randomized controlled trials
(Oklahoma State University Center for Health Sciences, 2019-02-22)
Introduction: The issue of research waste has been raised due to the fact that 85% of funding for biomedical research has been improperly utilized. A prominent issue is the frequency of randomized controlled trials (RCTs) ...
Calcium imagining and deep behavior analysis in fentanyl vapor self-administration and relapse
(Oklahoma State University Center for Health Sciences, 2023-02-17)
The prevalence of opioid use disorder (OUD) and overdose deaths have reached epidemic proportions and constitute a global crisis. In 2019 synthetic opioids, including fentanyl, were being used by 1.2% of the worldwide ...
Venom:antivenom immune complex binding assay using size-exclusion high-performance liquid chromatography (SE-HPLC)
(Oklahoma State University Center for Health Sciences, 2019-02-22)
The treatment of envenomation with effective snake antivenom immunoglobins has become a critical worldwide health issue. Current methods for testing the effectiveness of new antivenom mixtures in neutralizing venom ...