Search
Now showing items 41-50 of 58
Analysis of changing statistical significance from .05 to .005 in foot and ankle randomized controlled trials
(Oklahoma State University Center for Health Sciences, 2022-02-18)
Background: Misinterpretation of p-values in RCTs is extremely problematic since they are the core basis for high levels of recommendation in clinical practice guidelines, especially Orthopaedics. Benjamin et al. proposed ...
Patient-reported outcomes of firefighters using seven health and ability questionnaires
(Oklahoma State University Center for Health Sciences, 2022-02-18)
Background: Firefighting is among one of the most dangerous professions and requires exceptional physical fitness and focus while working. Patient-reported outcomes are a commonly used method to evaluate subjective health ...
Estimating a rural-urban PCP workload disparity: caring for smokers
(Oklahoma State University Center for Health Sciences, 2022-02-18)
Background: Smokers are concentrated in rural America. CDC reports 28.5% of rural Americans smoke versus 25.1% of urban Americans. The workload impact of those additional smokers in a rural primary care practice has not ...
Influence of COVID-19 on contraception: a cross-sectional analysis of disrupted clinical trials
(Oklahoma State University Center for Health Sciences, 2022-02-18)
Background: The COVID-19 pandemic exacerbated barriers to contraceptive services and disrupted the progression of ongoing clinical trials (CTs) in several fields of medicine1–4, including contraceptive care. Further, ...
Decreased serum levels of proBDNF, but not mature BDNF during adolescent oxycodone intoxication preceding long-term social neglect and harsh environmental conditions
(Oklahoma State University Center for Health Sciences, 2022-02-18)
Background: Adolescent opioid addiction is a global problem with a significant social and economic burden in the United States. Several studies have suggested that BDNF (mature BDNF) and its precursor play an essential ...
Proteomics study reveals a hydroxysteroid dehydrogenase (HSD) as a sex-based biomarker in Hepatitis C virus induced cirrhosis
(Oklahoma State University Center for Health Sciences, 2022-02-18)
Hepatitis C virus (HCV) infection-related inflammation, liver fibrosis and cirrhosis often lead to development of hepatocellular carcinoma (HCC). In the United States, 4.6 million people are infected with HCV. Studies show ...
Proteomics study reveals a gender-based ribosomal inflammatory biomarker in Hepatitis C virus induced cirrhosis
(Oklahoma State University Center for Health Sciences, 2022-02-18)
Hepatitis C Virus (HCV) infection is a major cause of Hepatocellular Carcinoma (HCC). Further, HCC is a leading cause of liver-related death world-wide linked to liver cirrhosis and chronic liver disease. Clinical evidence ...
Archaea in mammalian gut microbiomes
(Oklahoma State University Center for Health Sciences, 2022-02-18)
Background: Archaea are the most enigmatic domain of the three domains of life. Archaea are unique in that they share some characteristics with bacteria and others with eukaryotes while they are also distinct from these ...
Longitudinal changes to NIH Scientific Review Groups’ composition to address gender- and region-based disparities
(Oklahoma State University Center for Health Sciences, 2022-02-18)
Historically, participation in Scientific Research Groups, which are responsible for delegating federal funding for biomedical research (e.g. NIH R01 grants), has shown disproportionate gender and geographic biases. ...
Patient-reported outcomes are frequently incomplete in randomized controlled trials focused on alcohol use disorder: a meta-epidemiological analysis
(Oklahoma State University Center for Health Sciences, 2022-02-18)