The purpose of this study was to investigate how professional and personal experiences influence total life satisfaction of 261 university-affiliated people. An online survey was conducted to assess the relationships between perceived organizational support, burnout, communication technologies, personal responsibilities, enrichment between work and family, and overall life satisfaction. The results indicated work and family significantly influenced each other in addition to total life satisfaction. Supplemental hypotheses revealed perceived organizational support has a positive relationship with professional satisfaction. Burnout and communication technologies outside of work hours have a negative relationship with professional satisfaction. Work and family enrichment significantly influenced one another. Personal responsibilities were not significant of personal satisfaction in totality but did prove significant from specific individual questions on certain sample demographic traits.