dc.contributor.author | Zhao, Mengmeng | |
dc.contributor.author | Wang, Lingyan | |
dc.contributor.author | Li, Shitao | |
dc.date.accessioned | 2019-09-25T18:24:46Z | |
dc.date.available | 2019-09-25T18:24:46Z | |
dc.date.issued | 2017-08-01 | |
dc.identifier | oksd_zhao_influenzaavirus_2017 | |
dc.identifier.citation | Zhao, M., Wang, L., & Li, S. (2017). Influenza A virus-host protein interactions control viral pathogenesis. International Journal of Molecular Sciences, 18(8), Article 1673. https://doi.org/10.3390/ijms18081673 | |
dc.identifier.uri | https://hdl.handle.net/11244/321450 | |
dc.description.abstract | The influenza A virus (IAV), a member of the Orthomyxoviridae family, is a highly transmissible respiratory pathogen and represents a continued threat to global health with considerable economic and social impact. IAV is a zoonotic virus that comprises a plethora of strains with different pathogenic profiles. The different outcomes of viral pathogenesis are dependent on the engagement between the virus and the host cellular protein interaction network. The interactions may facilitate virus hijacking of host molecular machinery to fulfill the viral life cycle or trigger host immune defense to eliminate the virus. In recent years, much effort has been made to discover the virus-host protein interactions and understand the underlying mechanisms. In this paper, we review the recent advances in our understanding of IAV-host interactions and how these interactions contribute to host defense and viral pathogenesis. | |
dc.format | application/pdf | |
dc.language | en_US | |
dc.publisher | MDPI | |
dc.rights | This material has been previously published. In the Oklahoma State University Library's institutional repository this version is made available through the open access principles and the terms of agreement/consent between the author(s) and the publisher. The permission policy on the use, reproduction or distribution of the material falls under fair use for educational, scholarship, and research purposes. Contact Digital Resources and Discovery Services at lib-dls@okstate.edu or 405-744-9161 for further information. | |
dc.title | Influenza A virus-host protein interactions control viral pathogenesis | |
osu.filename | oksd_zhao_influenzaavirus_2017.pdf | |
dc.description.peerreview | Peer reviewed | |
dc.identifier.doi | 10.3390/ijms18081673 | |
dc.description.department | Physiological Sciences | |
dc.type.genre | Article | |
dc.type.material | Text | |
dc.subject.keywords | flu | |
dc.subject.keywords | host defense | |
dc.subject.keywords | protein interactome | |
dc.subject.keywords | virulence | |
dc.subject.keywords | virus-host interactions | |