Vegetation strongly influences exchanges of energy and moisture between land and atmosphere through (1) the vegetation's response to incoming radiation and its emission of longwave radiation (2) the vegetation's physical presence, and (3) the plant's transpiration. These processes affect the diurnal temperature range, processes in the atmospheric boundary layer, cloud cover, rainfall, differential heating, and atmospheric circulations. This paper overviews how vegetation interacts with surface energy and moisture budgets and reviews both observational and modelling studies that examine how vegetation affects weather and climate on the mesoscale (ie, phenomena 10s to 100s of kilometres in horizontal size).