Browsing OU - Theses by Author "O'Rear, Edgar"
Now showing items 1-7 of 7
-
Blood Damage Analysis using Computational Fluid Dynamics of Blood Flow through a Functioning and Malfunctioning Bileaflet Artificial Heart Valve
James, Madison (2018-08)Artificial heart valves are an invaluable tool to treat heart defects and diseases. However, these prosthetic devices may expose the blood to turbulent flow conditions leading to unnaturally high stress that can damage ... -
DROP PENETRATION MEASUREMENT OF ZnO AND TiO2 NANOPARTICLES FOR POTENTIAL ANTIBACTERIAL APPLICATIONS IN DENTAL ADHESIVES
Garner, Sabrina (2020-07-30)Despite all efforts carious lesions continues to be a significant problem in dentistry. Secondary caries is a biofilm-originated disease that typically occurs at the tooth-adhesive resin interface. According to previous ... -
EFFECTS OF FLOW RATE ON MESENCHYMAL STEM CELL OXYGEN CONSUMPTION RATES IN 3D BONE TISSUE ENGINEERED CONSTRUCTS CULTURED IN PERFUSION BIOREACTOR SYSTEMS
Felder, Michael (2019-05)Bone grafts comprise a multibillion dollar industry, with over a million grafts occurring each year around the world. These grafts are commonly autologous or allogenic. Autologous grafts are taken from the patient, and are ... -
Exploring hemolysis due to paravalvular leakage in artificial heart valves
Twitchell, Kyle (2020-12-18)Artificial heart valves require a surgical suture to keep them in place. These sutures can become infected or degrade over time, which can give rise to the phenomenon of paravalvular leakage. The defect compromising flow ... -
Simple modification method for the surface functionalization of poly (α-hydroxy ester) polymers
Murray, Jimmy David (2012)A vital component for the engineering of tissue constructs in vitro is a scaffold that allows cells to adhere and proliferate. Biomimetic scaffolds aim to enhance the regeneration of damaged tissue by mimicking the cells' ... -
STUDIES UTILIZING DECELLULARIZED HUMAN AMNIOTIC MEMBRANE AND SW-620 CELLS AS A PRELUDE TO 3D IN VITRO CULTURES
Narum, Melissa (2017)The prevalence of cancer in modern society has increased from 14.1 million new diagnoses and 8.2 million deaths in 2012 to an estimated 21.7 million new diagnoses and 13 million cancer-related deaths projected in 2030. The ... -
Utilizing Flow Perfusion Bioreactor Systems as Novel Platforms for Cancer Research
Bryant, Parker (2023-08-04)Cancer remains a leading cause of death worldwide, with no signs of slowing down. In 2023 alone, the projected number of deaths from cancer is 600,000, with projected incidences at almost 2 million. Mortality rates have ...