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dc.contributor.advisorPurdie, Neil
dc.contributor.authorAtkinson, William Marc
dc.date.accessioned2015-08-27T16:04:30Z
dc.date.available2015-08-27T16:04:30Z
dc.date.issued1983-05-01
dc.identifier.urihttps://hdl.handle.net/11244/16244
dc.description.abstractCircular Dichroism (CD), a nontraditional analytical technique, is evaluated for the analysis of nicotine and its major metabolite cotinine. A comparison of the CD and uv-visible methods for the analysis of nicotine in tobacco samples exemplifies many of the advantages the CD method has over other methods of analysis. The CD spectra of nicotine and cotinine are characterized and methods for the subsequent quantitative analysis are outlined. The binding constant for a nicotine-B-cyclodextrin complex is determined -and efforts to analyze a cotinine/nicotine binary mixture are described.
dc.formatapplication/pdf
dc.languageen_US
dc.publisherOklahoma State University
dc.rightsCopyright is held by the author who has granted the Oklahoma State University Library the non-exclusive right to share this material in its institutional repository. Contact Digital Library Services at lib-dls@okstate.edu or 405-744-9161 for the permission policy on the use, reproduction or distribution of this material.
dc.titleDirect Determination of Nicotine by Circular Dichroism Spectropolarimetry
dc.typetext
dc.contributor.committeeMemberMottola, H.A.
dc.contributor.committeeMemberMcGown, L. B.
osu.filenameThesis-1983-A878d.pdf
osu.accesstypeOpen Access
dc.description.departmentChemistry
dc.type.genreThesis


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